Evidence map›Paper›PMID 35270003›Full record

ArticleInternational journal of molecular sciences2022

Early Inactivation of Membrane Estrogen Receptor Alpha (ERα) Recapitulates the Endothelial Dysfunction of Aged Mouse Resistance Arteries.

Julie Favre, Emilie Vessieres, Anne-Laure Guihot, Linda Grimaud, Coralyne Proux, Laurent Loufrani, Françoise Lenfant, Coralie Fontaine, Jean-François Arnal, Daniel Henrion

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. The Role of Estrogen Receptors in Health and Disease.International journal of molecular sciences · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Julie FavreMitoVasc Department, Team 2 (CarMe) and CARFI Facility, Angers University, F-49045 Angers, France.ORCID 0000-0003-1044-0950
Emilie VessieresMitoVasc Department, Team 2 (CarMe) and CARFI Facility, Angers University, F-49045 Angers, France.
Anne-Laure GuihotMitoVasc Department, Team 2 (CarMe) and CARFI Facility, Angers University, F-49045 Angers, France.
Linda GrimaudMitoVasc Department, Team 2 (CarMe) and CARFI Facility, Angers University, F-49045 Angers, France.
Coralyne ProuxMitoVasc Department, Team 2 (CarMe) and CARFI Facility, Angers University, F-49045 Angers, France.
Laurent LoufraniMitoVasc Department, Team 2 (CarMe) and CARFI Facility, Angers University, F-49045 Angers, France.ORCID 0000-0003-3397-2335
Françoise LenfantInstitut National de la Santé et de la Recherche Médicale (INSERM), U1297, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III Paul Sabatier, CHU Rangueil (University Hospital) de Toulouse, F-31432 Toulouse, France.ORCID 0000-0003-0024-7241
Coralie FontaineInstitut National de la Santé et de la Recherche Médicale (INSERM), U1297, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III Paul Sabatier, CHU Rangueil (University Hospital) de Toulouse, F-31432 Toulouse, France.
Jean-François ArnalInstitut National de la Santé et de la Recherche Médicale (INSERM), U1297, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III Paul Sabatier, CHU Rangueil (University Hospital) de Toulouse, F-31432 Toulouse, France.ORCID 0000-0003-2229-6300
Daniel HenrionMitoVasc Department, Team 2 (CarMe) and CARFI Facility, Angers University, F-49045 Angers, France.ORCID 0000-0003-1094-0285
Centre National de la Recherche Scientifique · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

Agence Nationale de la Recherche ANR-18-CE14-0016-01Fondation de France 00086486Fondation pour la Recherche Médicale DEQ20160334924Fondation pour la Recherche Médicale DPC20171138957
6 · The paper itself

Abstract

Flow-mediated dilation (FMD) of resistance arteries is essential for tissue perfusion but it decreases with ageing. As estrogen receptor alpha (Erα encoded by

Indexed as

Estrogen Receptor alphaMesenteric ArteriesAgingAnimalsEstradiolMiceEstradiolEstrogen Receptor alphaageingendotheliumestrogen receptorsflow-mediated dilationresistance arteriesshear stress

Identifiers

PMID35270003
PMCPMC8911509
OpenAlexW4221088312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.