Evidence map›Paper›PMID 35269987›Full record

ArticleInternational journal of molecular sciences2022

The Anti-Proliferative and Apoptotic Effects of Rutaecarpine on Human Esophageal Squamous Cell Carcinoma Cell Line CE81T/VGH In Vitro and In Vivo.

Li-Yu Wang, Shu-Lan Yeh, Shih-Tien Hsu, Chao-Hsiang Chen, Chien-Chih Chen, Cheng-Hung Chuang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Li-Yu WangDepartment of Nutrition, Hungkuang University, Taichung 433304, Taiwan.
Shu-Lan YehDepartment of Nutrition, Chung Shan Medical University, Taichung 40201, Taiwan.
Shih-Tien HsuDepartment of Obstetrics and Gynecology and Women's Health, Taichung Veterans General Hospital, Taichung 40705, Taiwan.
Chao-Hsiang ChenKo Da Pharmaceutical Co., Ltd., Taoyuan City 32459, Taiwan.
Chien-Chih ChenDepartment of Cosmetic Science, Chang Gung University of Science and Technology, Taoyuan City 33303, Taiwan.
Cheng-Hung ChuangDepartment of Nutrition, Hungkuang University, Taichung 433304, Taiwan.ORCID 0000-0003-1963-1825
Chang Gung University of Science and Technology · TWChung Shan Medical University · TWHungkuang University · TWLing Tung University · TWNational Chung Hsing University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overall five-year survival rate for patients with esophageal cancer is low (15 to 25%) because of the poor prognosis at earlier stages. Rutaecarpine (RTP) is a bioalkaloid found in the traditional Chinese herb

Indexed as

Esophageal NeoplasmsEsophageal Squamous Cell CarcinomaAnimalsApoptosisbcl-2-Associated X ProteinCaspase 3Caspase 9Cell Line, TumorCell ProliferationHumansIndole AlkaloidsMiceProto-Oncogene Proteins c-bcl-2QuinazolinesQuinazolinonesTumor Suppressor Protein p53bcl-2-Associated X ProteinCaspase 3Caspase 9Indole AlkaloidsProto-Oncogene Proteins c-bcl-2QuinazolinesQuinazolinonesrutecarpineTumor Suppressor Protein p53apoptosisesophageal cancerEvodia rutaecarpap53 generutaecarpine

Identifiers

PMID35269987
PMCPMC8911365
OpenAlexW4221137916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.