Evidence map›Paper›PMID 35269725›Full record

ArticleInternational journal of molecular sciences2022

The Finely Coordinated Action of SSB and NurA/HerA Complex Strictly Regulates the DNA End Resection Process in

Mariarosaria De Falco, Alessandra Porritiello, Federica Rota, Viviana Scognamiglio, Amina Antonacci, Giovanni Del Monaco, Mariarita De Felice

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mariarosaria De FalcoInstitute of Biosciences and BioResources, Consiglio Nazionale delle Ricerche, 80131 Naples, Italy.ORCID 0000-0002-6298-3431
Alessandra PorritielloInstitute of Biosciences and BioResources, Consiglio Nazionale delle Ricerche, 80131 Naples, Italy.
Federica RotaInstitute of Biosciences and BioResources, Consiglio Nazionale delle Ricerche, 80131 Naples, Italy.
Viviana ScognamiglioDepartment of Chemical Sciences and Materials Technologies, Institute of Crystallography, National Research Council, Via Salaria Km 29,300, Monterotondo, 00015 Rome, Italy.
Amina AntonacciDepartment of Chemical Sciences and Materials Technologies, Institute of Crystallography, National Research Council, Via Salaria Km 29,300, Monterotondo, 00015 Rome, Italy.
Giovanni Del MonacoInstitute of Biosciences and BioResources, Consiglio Nazionale delle Ricerche, 80131 Naples, Italy.
Mariarita De FeliceInstitute of Biosciences and BioResources, Consiglio Nazionale delle Ricerche, 80131 Naples, Italy.ORCID 0000-0002-4906-780X
Institute of Biosciences and Bioresources · ITNational Research Council · IT

Funding

"Attività formative nell'ambito dei progetti di alternanza scuola lavoro"-progetto CNR DBA.AD006.025
6 · The paper itself

Abstract

Generation of the 3' overhang is a critical step during homologous recombination (HR) and replication fork rescue processes. This event is usually performed by a series of DNA nucleases and/or helicases. The nuclease NurA and the ATPase HerA, together with the highly conserved MRE11/RAD50 proteins, play an important role in generating 3' single-stranded DNA during archaeal HR. Little is known, however, about HerA-NurA function and activation of this fundamental and complicated DNA repair process. Herein, we analyze the functional relationship among NurA, HerA and the single-strand binding protein SSB from

Indexed as

Archaeal ProteinsSulfolobus solfataricusDNADNA HelicasesDNA RepairDNA, Single-StrandedArchaeal ProteinsDNADNA HelicasesDNA, Single-StrandedArchaeaDNA helicaseDNA repairHRnucleaseSSB

Identifiers

PMID35269725
PMCPMC8910471
OpenAlexW4214621036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.