Evaluation of Myeloperoxidase as Target for Host-Directed Therapy in Tuberculosis In Vivo.

Lara C Linnemann, Ulrich E Schaible, Tobias K Dallenga

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

0.4field-weighted citation impact, top 43% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

Neutrophil extracellular traps in asthma and chronic obstructive pulmonary disease: pathogenic roles, and therapeutic opportunities.Frontiers in immunology · 2026
Review
Classification and characterisation of extracellular vesicles-related tuberculosis subgroups and immune cell profiles.Journal of cellular and molecular medicine · 2023
Article
Human neutrophilsImmunological reviews · 2023
Review
Non-Canonical Functions of Myeloperoxidase in Immune Regulation, Tissue Inflammation and Cancer.International journal of molecular sciences · 2022
Review
Cellular and Molecular Mechanisms in Mycobacterial Infection.International journal of molecular sciences · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lara C LinnemannDivision Cellular Microbiology, Research Center Borstel, 23845 Borstel, Germany.

Ulrich E SchaibleDivision Cellular Microbiology, Research Center Borstel, 23845 Borstel, Germany.ORCID 0000-0002-6638-7282

Tobias K DallengaDivision Cellular Microbiology, Research Center Borstel, 23845 Borstel, Germany.ORCID 0000-0002-1737-0687

German Center for Infection Research · DE

Funding

Deutsche Forschungsgemeinschaft DFG IRTG-1911German Center for Infection Research TTU-TB

6 · The paper itself

Abstract

Due to the rise of tuberculosis cases infected with multi and extensively drug-resistant

Indexed as

Mycobacterium tuberculosisTuberculosisAnimalsAnti-Bacterial AgentsDisease Models, AnimalMiceMice, Inbred StrainsNecrosisNeutrophilsPeroxidaseAnti-Bacterial AgentsPeroxidasehost-directed therapyMycobacterium tuberculosismyeloperoxidaseneutrophilstuberculosis

Identifiers

PMID35269694

DOI10.3390/ijms23052554

PMCPMC8910451

OpenAlexW4214726095

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.