Evidence map›Paper›PMID 35269596›Full record

ArticleInternational journal of molecular sciences2022

Production of an Active, Human Membrane Protein in

Minttu S Virolainen, Cecilie L Søltoft, Per A Pedersen, Lars Ellgaard

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Minttu S VirolainenLinderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen, Denmark.
Cecilie L SøltoftLinderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen, Denmark.
Per A PedersenDepartment of Biology, University of Copenhagen, Universitetsparken 15, DK-2200 Copenhagen, Denmark.ORCID 0000-0001-8648-9748
Lars EllgaardLinderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen, Denmark.ORCID 0000-0002-7018-0137
University of Copenhagen · DK

Funding

Danish council for Independent Research | Natural Sciences DFF-6108-00165Novo Nordisk Foundation NNF13OC0006217Villum Foundation 95-300-13733
6 · The paper itself

Abstract

The human Fic domain-containing protein (FICD) is a type II endoplasmic reticulum (ER) membrane protein that is important for the maintenance of ER proteostasis. Structural and in vitro biochemical characterisation of FICD AMPylase and deAMPylase activity have been restricted to the soluble ER-luminal domain produced in

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsEndoplasmic ReticulumHumansMembrane ProteinsNucleotidyltransferasesProtein Processing, Post-TranslationalMembrane ProteinsNucleotidyltransferasesSaccharomyces cerevisiae ProteinsAMPylationFICDFic proteinsmembrane protein purificationrecombinant protein expressionSaccharomyces cerevisiae

Identifiers

PMID35269596
PMCPMC8910494
OpenAlexW4213431261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.