Evidence map›Paper›PMID 35269487›Full record

ArticleCells2022

Mechanisms of A-Type Lamin Targeting to Nuclear Ruptures Are Disrupted in

Rhiannon M Sears, Kyle J Roux

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  12. DNA density is a better indicator of a nuclear bleb than lamin B loss.bioRxiv : the preprint server for biology · 2024
    Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rhiannon M SearsEnabling Technologies Group, Sanford Research, Sioux Falls, SD 57104, USA.ORCID 0000-0002-5171-5036
Kyle J RouxEnabling Technologies Group, Sanford Research, Sioux Falls, SD 57104, USA.ORCID 0000-0001-7530-5528
University of South Dakota · US

Funding

Yeast 2 HybridP20GM103620 · NIGMS · SANFORD RESEARCH/USD · PI ROUX, KYLE J · 2013 to 2023
$24.2M
The Impact of PD-1 Inhibition on Immune-Response to ChemoradiotherapyP20GM103548 · NIGMS · SANFORD RESEARCH/USD · PI MISKIMINS, W KEITH · 2012 to 2020
$20.8M
Evolution and application of proximity protein labelingR35GM126949 · NIGMS · SANFORD RESEARCH/USD · PI ROUX, KYLE J · 2018 to 2022
$2.0M
Developing methods for proximity-dependent protein labelingR01GM102203 · NIGMS · SANFORD RESEARCH/USD · PI ROUX, KYLE J · 2013 to 2017
$1.5M
NIGMS NIH HHS P20 GM103548NIGMS NIH HHS P20 GM103620NIGMS NIH HHS R01 GM102203NIGMS NIH HHS R35 GM126949
6 · The paper itself

Abstract

Mutations in the genes

Indexed as

ProgeriaCell NucleusHumansIntermediate Filament ProteinsLamin Type AMembrane ProteinsMutationNuclear EnvelopeIntermediate Filament ProteinsLamin Type ALMNA protein, humanMembrane ProteinsBAFBANF1HGPSlaminLMNANGPSnuclear envelopenuclear ruptureprogeria

Identifiers

PMID35269487
PMCPMC8909658
OpenAlexW4221022264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.