Evidence map›Paper›PMID 35269410›Full record

ArticleCells2022

Long-Term Subjective and Objective Assessment of Smell and Taste in COVID-19.

Andrea Ciofalo, Carlo Cavaliere, Simonetta Masieri, Alessandra Di Chicco, Irene Fatuzzo, Federica Lo Re, Silvia Baroncelli, Elona Begvarfaj, Andrea Adduci, Ivano Mezzaroma and 5 more

Abstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. The long-term effect of COVID-19 infection on olfaction and taste; a prospective analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Observational
  5. Article
  6. Subjective versus Psychophysical Measures of Chemosensory Alterations following COVID-19.ORL; journal for oto-rhino-laryngology and its related specialties · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Andrea CiofaloDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.
Carlo CavaliereDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-0378-8935
Simonetta MasieriDepartment of Oral and Maxillofacial Sciences, Sapienza University, 00161 Rome, Italy.
Alessandra Di ChiccoDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.
Irene FatuzzoDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.ORCID 0000-0001-9194-1444
Federica Lo ReDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.ORCID 0000-0003-2579-1219
Silvia BaroncelliNational Centre for Global Heath, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-2050-9037
Elona BegvarfajDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.
Andrea AdduciDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.
Ivano MezzaromaDepartment of Translational and Precision Medicine, Sapienza University, 00185 Rome, Italy.ORCID 0000-0003-2855-6425
Claudio Maria MastroianniDepartment of Public Health and Infectious Diseases, Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-1286-467X
Marco de VincentiisDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.
Antonio GrecoDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.
Loris ZamaiDepartment of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy.ORCID 0000-0002-4361-1026
Marco ArticoDepartment of Sense Organs, Sapienza University, 00161 Rome, Italy.ORCID 0000-0002-8786-7007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the first clinical symptoms of the SARS-CoV-2 infection is olfactory−gustatory deficit; this continues for weeks and, in some cases, can be persistent. We prospectively evaluated 162 patients affected by COVID-19 using a visual analogue scale (VAS) for nasal and olfactory−gustatory symptoms. Patients were checked after 7, 14, 21, 28, 90, and 180 days. A total of 118 patients (72.8%) reported an olfactory VAS < 7 at baseline (group B), and 44 (27.2%) reported anosmia (VAS ≥ 7) (group A) and underwent the Brief Smell Identification Test (B-SIT) and Burghart Taste Strips (BTS) to quantify the deficit objectively and repeated the tests to confirm the sense recovery. Group A patients showed B-SIT anosmia and hyposmia in 44.2% and 55.8% of cases, respectively. A total of 88.6% of group A patients reported ageusia with VAS ≥ 7, and BTS confirmed 81.8% of ageusia and 18.2% of hypogeusia. VAS smell recovery was recorded starting from 14 days, with normalization at 28 days. The 28-day B-SIT score showed normosmia in 90.6% of group A patients. The mean time for full recovery (VAS = 0) was shorter in group B (22.9 days) than in group A (31.9 days). Chemosensory deficit is frequently the first symptom in patients with COVID-19, and, in most cases, recovery occurs after four weeks.

Indexed as

AgeusiaCOVID-19Olfaction DisordersAnosmiaHumansSARS-CoV-2SmellTasteB-SITCOVID-19smelltastetaste strips

Identifiers

PMID35269410
PMCPMC8909596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.