Evidence map›Paper›PMID 35269381›Full record

ArticleCells2022

Annexin-A1-Derived Peptide Ac2-26 Suppresses Allergic Airway Inflammation and Remodelling in Mice.

Tatiana Paula Teixeira Ferreira, Fernanda Verdini Guimarães, Yago Amigo Pinho Jannini Sá, Natalia Barreto da Silva Ribeiro, Ana Carolina Santos de Arantes, Vinicius de Frias Carvalho, Lirlândia Pires Sousa, Mauro Perretti, Marco Aurélio Martins, Patrícia Machado Rodrigues E Silva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Loss of Endothelial Annexin A1 Aggravates Inflammation-Induched Vascular Aging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Tatiana Paula Teixeira FerreiraLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Fernanda Verdini GuimarãesLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Yago Amigo Pinho Jannini SáLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Natalia Barreto da Silva RibeiroLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Ana Carolina Santos de ArantesLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Vinicius de Frias CarvalhoLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Lirlândia Pires SousaFaculty of Pharmacy, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-1042-9762
Mauro PerrettiDepartment of Biochemical Pharmacology, The William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.ORCID 0000-0003-2068-3331
Marco Aurélio MartinsLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Patrícia Machado Rodrigues E SilvaLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.
Fundação Oswaldo Cruz · BRQueen Mary University of London · GBUniversidade Federal de Minas Gerais · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 01700/2020-8Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 304080/2013-6Fundação Carlos Chagas de Apoio à Pesquisa do Estado do Rio de Janeiro (FAPERJ) E-26/202.884/2018; E-26/010.000983/2019Oswaldo Cruz Foundation INOVA - VPPCB-007-FIO-18-2-75
6 · The paper itself

Abstract

Annexin-A1 (AnxA1) and its N-terminal derived peptide Ac2-26 regulate the inflammatory response in several experimental models of disorders. This study evaluated the effect of endogenous AnxA1 and its N-terminal peptide Acetyl 2-26 (Ac2-26) on allergic asthma triggered by house dust mite (HDM) extract in mice.

Indexed as

AsthmaInflammationAllergensAnimalsCytokinesFibrosisMicePeptidesAllergensCytokinesPeptidesallergic asthmainflammationlungpeptide Ac2-26remodellingtherapy

Identifiers

PMID35269381
PMCPMC8909467
OpenAlexW4214623622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.