Evidence map›Paper›PMID 35269242›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Magnetic Composites of Dextrin-Based Carbonate Nanosponges and Iron Oxide Nanoparticles with Potential Application in Targeted Drug Delivery.

Fabrizio Caldera, Roberto Nisticò, Giuliana Magnacca, Adrián Matencio, Yousef Khazaei Monfared, Francesco Trotta

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Design, characterization, andRSC advances · 2025
    Article
  3. Review
  4. Synthesis of Magnetic Luminescent Nanoparticle FeIndian journal of microbiology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fabrizio CalderaDepartment of Chemistry, NIS Centre, University of Torino, Via P. Giuria 7, 10125 Torino, Italy.ORCID 0000-0003-2581-0555
Roberto NisticòDepartment of Materials Science, University of Milano-Bicocca, Via R. Cozzi 55, 20125 Milano, Italy.ORCID 0000-0001-8986-5542
Giuliana MagnaccaDepartment of Chemistry, NIS Centre, University of Torino, Via P. Giuria 7, 10125 Torino, Italy.ORCID 0000-0002-3798-5232
Adrián MatencioDepartment of Chemistry, NIS Centre, University of Torino, Via P. Giuria 7, 10125 Torino, Italy.ORCID 0000-0001-8203-0673
Yousef Khazaei MonfaredDepartment of Chemistry, NIS Centre, University of Torino, Via P. Giuria 7, 10125 Torino, Italy.ORCID 0000-0002-1171-8670
Francesco TrottaDepartment of Chemistry, NIS Centre, University of Torino, Via P. Giuria 7, 10125 Torino, Italy.
University of Turin · ITUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetically driven nanosponges with potential application as targeted drug delivery systems were prepared via the addition of magnetite nanoparticles to the synthesis of cyclodextrin and maltodextrin polymers crosslinked with 1,1'-carbonyldiimidazole. The magnetic nanoparticles were obtained separately via a coprecipitation mechanism involving inorganic iron salts in an alkaline environment. Four composite nanosponges were prepared by varying the content of magnetic nanoparticles (5 wt% and 10 wt%) in the cyclodextrin- and maltodextrin-based polymer matrix. The magnetic nanosponges were then characterised by FTIR, TGA, XRD, FESEM, and HRTEM analysis. The magnetic properties of the nanosponges were investigated via magnetisation curves collected at RT. Finally, the magnetic nanosponges were loaded with doxorubicin and tested as a drug delivery system. The nanosponges exhibited a loading capacity of approximately 3 wt%. Doxorubicin was released by the loaded nanosponges with sustained kinetics over a prolonged period of time.

Indexed as

cyclodextrindextrin nanospongesdoxorubiciniron oxide nanoparticlesmagnetic nanocompositesmaltodextrintargeted drug delivery

Identifiers

PMID35269242
PMCPMC8911700
OpenAlexW4214507334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.