Evidence map›Paper›PMID 35268997›Full record

ArticleMaterials (Basel, Switzerland)2022

Novel, Inexpensive, and Scalable Amyloid Fibril Formation Method.

Ethan Hessick, Milind Pawar, Reid Souchereau, Emma Schmitz, Pelagia-Irene Gouma

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ethan HessickAdvanced Ceramics Research Laboratory, Department of Materials Science and Engineering, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-3895-1496
Milind PawarAdvanced Ceramics Research Laboratory, Department of Materials Science and Engineering, The Ohio State University, Columbus, OH 43210, USA.
Reid SouchereauAdvanced Ceramics Research Laboratory, Department of Materials Science and Engineering, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-0163-1368
Emma SchmitzAdvanced Ceramics Research Laboratory, Department of Materials Science and Engineering, The Ohio State University, Columbus, OH 43210, USA.
Pelagia-Irene GoumaAdvanced Ceramics Research Laboratory, Department of Materials Science and Engineering, The Ohio State University, Columbus, OH 43210, USA.
The Ohio State University · US

Funding

The Orton Chair Funds at The Ohio State University N/A
6 · The paper itself

Abstract

Wheat flour was used as a source of protein for the in vitro synthesis of Amyloid fibrils to develop a novel and inexpensive fabrication method. Amyloid fibrillation was confirmed by Thioflavin T Fluorescence, using confocal microscopy. A morphological study was carried out by transmission electron microscopy (TEM), which revealed the high aspect ratio of the amyloid fibrils formed via a novel process. An application of the amyloid fibers produced by the novel method is shown to be melatonin sensing. Tests showed that the amyloid samples had a measurable color variation dependent on the melatonin concentration. This newly derived process could prove to be a cost-effective tool for future nano-biomaterial applications in commercial and research settings.

Indexed as

amyloidinexpensivemelatonin biosensingsynthesis

Identifiers

PMID35268997
PMCPMC8911616
OpenAlexW4214533756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.