Evidence map›Paper›PMID 35268986›Full record

ArticleMaterials (Basel, Switzerland)2022

Synthesis and Characterization of Magnetic Composite Theragnostics by Nano Spray Drying.

Caio José Perecin, Xavier Pierre Marie Gratens, Valmir Antônio Chitta, Patrícia Leo, Adriano Marim de Oliveira, Sérgio Akinobu Yoshioka, Natália Neto Pereira Cerize

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Caio José PerecinSão Carlos Institute of Chemistry, University of São Paulo, São Carlos 13566-590, SP, Brazil.
Xavier Pierre Marie GratensInstitute of Physics, University of São Paulo, São Paulo 05508-090, SP, Brazil.ORCID 0000-0003-3732-0684
Valmir Antônio ChittaInstitute of Physics, University of São Paulo, São Paulo 05508-090, SP, Brazil.
Patrícia LeoBionanomanufacturing Center, Technological Research Institute, São Paulo 05508-070, SP, Brazil.
Adriano Marim de OliveiraBionanomanufacturing Center, Technological Research Institute, São Paulo 05508-070, SP, Brazil.
Sérgio Akinobu YoshiokaSão Carlos Institute of Chemistry, University of São Paulo, São Carlos 13566-590, SP, Brazil.ORCID 0000-0003-0016-733X
Natália Neto Pereira CerizeBionanomanufacturing Center, Technological Research Institute, São Paulo 05508-070, SP, Brazil.
Universidade de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88882.331022/2018-01
6 · The paper itself

Abstract

Composites of magnetite nanoparticles encapsulated with polymers attract interest for many applications, especially as theragnostic agents for magnetic hyperthermia, drug delivery, and magnetic resonance imaging. In this work, magnetite nanoparticles were synthesized by coprecipitation and encapsulated with different polymers (Eudragit S100, Pluronic F68, Maltodextrin, and surfactants) by nano spray drying technique, which can produce powders of nanoparticles from solutions or suspensions. Transmission and scanning electron microscopy images showed that the bare magnetite nanoparticles have 10.5 nm, and after encapsulation, the particles have approximately 1 μm, with size and shape depending on the material's composition. The values of magnetic saturation by SQUID magnetometry and mass residues by thermogravimetric analysis were used to characterize the magnetic content in the materials, related to their magnetite/polymer ratios. Zero-field-cooling and field-cooling (ZFC/FC) measurements showed how blocking temperatures of the powders of the composites are lower than that of bare magnetite, possibly due to lower magnetic coupling, being an interesting system to study magnetic interactions of nanoparticles. Furthermore, studies of cytotoxic effect, hydrodynamic size, and heating capacity for hyperthermia (according to the application of an alternate magnetic field) show that these composites could be applied as a theragnostic material for a non-invasive administration such as nasal.

Indexed as

compositesmagnetic hyperthermiamagnetic nanoparticlesnano spray dryingsuperparamagnetismtheragnostic

Identifiers

PMID35268986
PMCPMC8911310
OpenAlexW4214667709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.