Evidence map›Paper›PMID 35268803›Full record

ArticleMolecules (Basel, Switzerland)2022

Phosphodiester Silybin Dimers Powerful Radical Scavengers: A Antiproliferative Activity on Different Cancer Cell Lines.

Valeria Romanucci, Rita Pagano, Antonio Lembo, Domenica Capasso, Sonia Di Gaetano, Armando Zarrelli, Giovanni Di Fabio

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Valeria RomanucciDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Napoli, Italy.ORCID 0000-0003-0317-5140
Rita PaganoDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Napoli, Italy.ORCID 0000-0002-9402-389X
Antonio LemboDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Napoli, Italy.
Domenica CapassoInteruniversity Research Centre on Bioactive Peptides (CIRPeB), University of Naples "Federico II", Via Mezzocannone 16, 80134 Napoli, Italy.ORCID 0000-0001-7201-3431
Sonia Di GaetanoInteruniversity Research Centre on Bioactive Peptides (CIRPeB), University of Naples "Federico II", Via Mezzocannone 16, 80134 Napoli, Italy.ORCID 0000-0001-5523-3619
Armando ZarrelliDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Napoli, Italy.ORCID 0000-0001-7866-821X
Giovanni Di FabioDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Napoli, Italy.ORCID 0000-0003-2912-4827
University of Naples Federico II · ITAssociazione Italiana Vulvodinia Onlus · ITCentro Interuniversitario di Ricerca sui Peptidi Bioattivi · ITInstitute of Biostructure and Bioimaging · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silibinin is the main biologically active component of silymarin extract and consists of a mixture 1:1 of two diastereoisomeric flavonolignans, namely silybin A (

Indexed as

NeoplasmsSilymarinAntioxidantsCell LineQuercetinSilybinAntioxidantsQuercetinSilybinSilymarinapoptosisflavonolignan dimersleukemia cellsradical scavenger of ROSsilibininsilybin

Identifiers

PMID35268803
PMCPMC8911775
OpenAlexW4220751273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.