Evidence map›Paper›PMID 35268769›Full record

ReviewMolecules (Basel, Switzerland)2022

Nanocarriers as Active Ingredients Enhancers in the Cosmetic Industry-The European and North America Regulation Challenges.

Cristiana Oliveira, Cristina Coelho, José A Teixeira, Pedro Ferreira-Santos, Claudia M Botelho

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

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  11. Molecules (Basel, Switzerland) · 2025
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  20. Encapsulation of MicroalgaeMarine drugs · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cristiana OliveiraCEB-Center of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Cristina CoelhoMesosystem S.A., Rua de Júlio Dinis 228, 4050-371 Porto, Portugal.
José A TeixeiraCEB-Center of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-4918-3704
Pedro Ferreira-SantosCEB-Center of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-9427-4605
Claudia M BotelhoCEB-Center of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0001-8221-419X
University of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

"Flawless skin is the most universally desired human feature" is an iconic statement by Desmond Morris. Skin indicates one´s health and is so important that it affects a person's emotional and psychological behavior, these facts having propelled the development of the cosmetics industry. It is estimated that in 2023, this industry will achieve more than 800 billion dollars. This boost is due to the development of new cosmetic formulations based on nanotechnology. Nanocarriers have been able to solve problems related to active ingredients regarding their solubility, poor stability, and release. Even though nanocarriers have evident benefits, they also present some problems related to the high cost, low shelf life, and toxicity. Regulation and legislation are two controversial topics regarding the use of nanotechnology in the field of cosmetics. In this area, the U.S. FDA has taken the lead and recommended several biosafety studies and post-market safety evaluations. The lack of a global definition that identifies nanomaterials as a cosmetic ingredient is a hindrance to the development of global legislation. In the EU, the legislation regarding the biosafety of nanomaterials in cosmetics is stricter. "The cost is not the only important issue, safety and the application of alternative testing methods for toxicity are of crucial importance as well".

Indexed as

CosmeticsNanostructuresDrug CompoundingHumansNanotechnologySkinCosmeticscosmeticsdelivery systemsEuropelegislationnanotechnologyUSA

Identifiers

PMID35268769
PMCPMC8911847
OpenAlexW4214835576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.