Evidence map›Paper›PMID 35268562›Full record

ArticleMolecules (Basel, Switzerland)2022

New Red-Shifted 4-Styrylcoumarin Derivatives as Potential Fluorescent Labels for Biomolecules.

Raquel Eustáquio, João P Prates Ramalho, Ana T Caldeira, António Pereira

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raquel EustáquioHercules Laboratory, University of Évora, Largo Marquês de Marialva 8, 7000-809 Évora, Portugal.
João P Prates RamalhoChemistry Department, School of Sciences and Technology, University of Évora, Rua Romão Ramalho 59, 7000-671 Évora, Portugal.ORCID 0000-0003-4419-6431
Ana T CaldeiraHercules Laboratory, University of Évora, Largo Marquês de Marialva 8, 7000-809 Évora, Portugal.ORCID 0000-0001-5409-6990
António PereiraHercules Laboratory, University of Évora, Largo Marquês de Marialva 8, 7000-809 Évora, Portugal.
University of Évora · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Important scientific areas, such as cellular biology, medicine, pharmacy, and environmental sciences, are dependent on very sensitive analytical techniques to track and detect biomolecules. In this work, we develop a simple, low-cost and effective synthetic strategy to produce new red-shifted 4-styrylcoumarin derivatives as promising inexpensive fluorescent labels for biomolecules. The extension of the delocalized π-electron system results in bathochromic shifts in these new coumarin derivatives, which also present large Stokes shifts. In addition, density functional theory and time-dependent density functional theory calculations helped to rationalize the photophysical properties observed by the experimental results.

Indexed as

CoumarinsFluorescent DyesDensity Functional TheoryMolecular StructureSpectrometry, FluorescenceCoumarinsFluorescent Dyes4-styrylcoumarin derivativesbiomolecules labelingcoumarinfluorescent labelslarge Stokes shifts

Identifiers

PMID35268562
PMCPMC8912076
OpenAlexW4214670186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.