Evidence map›Paper›PMID 35268482›Full record

ReviewJournal of clinical medicine2022

Risk Factors of Rejection in Renal Transplant Recipients: A Narrative Review.

Hani Oweira, Ali Ramouz, Omid Ghamarnejad, Elias Khajeh, Sadeq Ali-Hasan-Al-Saegh, Rajan Nikbakhsh, Christoph Reißfelder, Nuh Rahbari, Arianeb Mehrabi, Mahmoud Sadeghi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Effects ofCurrent pharmaceutical design · 2024
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. [Therapeutic response and monitoring of antibody-mediated renal graft rejection].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hani OweiraDepartment of Surgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Ali RamouzDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Omid GhamarnejadDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Elias KhajehDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Sadeq Ali-Hasan-Al-SaeghDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Rajan NikbakhshDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Christoph ReißfelderDepartment of Surgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Nuh RahbariDepartment of Surgery, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Arianeb MehrabiDepartment of General, Visceral, and Transplantation Surgery, University of Heidelberg, 69120 Heidelberg, Germany.
Mahmoud SadeghiDepartment of Transplantation Immunology, University of Heidelberg, 69120 Heidelberg, Germany.
Heidelberg University · DEUniversity Medical Centre Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple factors influence graft rejection after kidney transplantation. Pre-operative factors affecting graft function and survival include donor and recipient characteristics such as age, gender, race, and immunologic compatibility. In addition, several peri- and post-operative parameters affect graft function and rejection, such as cold and warm ischemia times, and post-operative immunosuppressive treatment. Exposure to non-self-human leucocyte antigens (HLAs) prior to transplantation up-regulates the recipient's immune system. A higher rate of acute rejection is observed in transplant recipients with a history of pregnancies or significant exposure to blood products because these patients have higher panel reactive antibody (PRA) levels. Identifying these risk factors will help physicians to reduce the risk of allograft rejection, thereby promoting graft survival. In the current review, we summarize the existing literature on donor- and recipient-related risk factors of graft rejection and graft loss following kidney transplantation.

Indexed as

kidney transplantationrecipientrejection

Identifiers

PMID35268482
PMCPMC8911293
OpenAlexW4214935529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.