Evidence map›Paper›PMID 35268463›Full record

ArticleJournal of clinical medicine2022

Clinical Outcomes in Patients Aged 80 Years or Older Receiving Non-Invasive Respiratory Support for Hypoxemic Acute Respiratory Failure Consequent to COVID-19.

Andrea Vianello, Nello De Vita, Lorenza Scotti, Gabriella Guarnieri, Marco Confalonieri, Valeria Bonato, Beatrice Molena, Carlo Maestrone, Gianluca Airoldi, Carlo Olivieri and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Andrea VianelloDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Gallucci, 13, 35121 Padova, Italy.ORCID 0000-0002-8790-6029
Nello De VitaDipartimento di Medicina Traslazionale, Università del Piemonte Orientale, Via Solaroli, 17, 28100 Novara, Italy.ORCID 0000-0003-3218-8653
Lorenza ScottiDipartimento di Medicina Traslazionale, Università del Piemonte Orientale, Via Solaroli, 17, 28100 Novara, Italy.
Gabriella GuarnieriDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Gallucci, 13, 35121 Padova, Italy.
Marco ConfalonieriPneumologia, Azienda Sanitaria Universitaria Giuliano Isontina, Via Giacomo Puccini, 50, 34148 Trieste, Italy.ORCID 0000-0002-4791-768X
Valeria BonatoDepartment of Anesthesia and Intensive Care, Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Via Venezia, 16, 15121 Alessandria, Italy.
Beatrice MolenaDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Gallucci, 13, 35121 Padova, Italy.
Carlo MaestroneAnestesia Rianimazione ASL VCO, Dipartimento Chirurgico, Presidio Ospedaliero Domodossola e Verbania, Largo Caduti Lager Nazisti, 1, 28845 Domodossola, Italy.
Gianluca AiroldiMedicina Interna, Ospedale Ss. Trinità, Viale Zoppis, 10, 28021 Borgomanero, Italy.ORCID 0000-0003-4551-1528
Carlo OlivieriDepartment of Anesthesia and Critical Care, Azienda Ospedaliera Sant'Andrea, Corso M. Abbiate, 21, 13100 Vercelli, Italy.
Pier Paolo SainaghiDipartimento di Medicina Traslazionale, Università del Piemonte Orientale, Via Solaroli, 17, 28100 Novara, Italy.ORCID 0000-0001-8322-9158
Federico LionelloDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Gallucci, 13, 35121 Padova, Italy.
Giovanna ArcaroDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, Via Gallucci, 13, 35121 Padova, Italy.
Francesco Della CorteDipartimento di Medicina Traslazionale, Università del Piemonte Orientale, Via Solaroli, 17, 28100 Novara, Italy.
Paolo NavalesiIstituto di Anestesia e Rianimazione, Dipartimento di Medicina-DIMED-Università di Padova, Azienda Ospedale-Università di Padova, Via Gallucci, 13, 35121 Padova, Italy.ORCID 0000-0002-3733-3453
Rosanna VaschettoDipartimento di Medicina Traslazionale, Università del Piemonte Orientale, Via Solaroli, 17, 28100 Novara, Italy.ORCID 0000-0003-4625-4367

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the clinical outcome of octogenarian patients hospitalised for COVID-19 is very poor, here we assessed the clinical characteristics and outcomes of patients aged 80 year or older hospitalised for COVID-19 receiving non-invasive respiratory support (NIRS). A multicentre, retrospective, observational study was conducted in seven hospitals in Northern Italy. All patients aged ≥80 years with COVID-19 associated hypoxemic acute respiratory failure (hARF) undergoing NIRS between 24 February 2020, and 31 March 2021, were included. Out of 252 study participants, 156 (61.9%) and 163 (64.6%) died during hospital stay and within 90 days from hospital admission, respectively. In this case, 228 (90.5%) patients only received NIRS (NIRS group), while 24 (9.5%) were treated with invasive mechanical ventilation (IMV) after NIRS failure (NIRS+IMV group). In-hospital mortality did not significantly differ between NIRS and NIRS+IMV group (61.0% vs. 70.8%, respectively;

Indexed as

acute respiratory failureCOVID-19non-invasive respiratory supportoctogenarian patients

Identifiers

PMID35268463
PMCPMC8911338

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.