Evidence map›Paper›PMID 35268392›Full record

ArticleJournal of clinical medicine2022

Prevalence and Prognostic Factors of Stress Hyperglycemia in a Pediatric Population with Acute Illness in Greece-A Prospective Observational Study.

Emmanouil Korakas, Theodoros Argyropoulos, Georgia-Angeliki Koliou, Aristofanis Gikas, Aikaterini Kountouri, Stavroula Kostaridou Nikolopoulou, Panagiotis Plotas, Konstantinos Kontoangelos, Ignatios Ikonomidis, Nikolaos P E Kadoglou and 2 more

Open access · goldAbstract read
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In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Emmanouil KorakasSecond Department of Internal Medicine and Research Institute, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0002-7813-5488
Theodoros ArgyropoulosDepartment of Paediatrics, Penteli Children's Hospital, 15236 Athens, Greece.
Georgia-Angeliki KoliouSecond Department of Internal Medicine and Research Institute, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Aristofanis GikasHealth Center of Kalivia, 19010 Athens, Greece.
Aikaterini KountouriSecond Department of Internal Medicine and Research Institute, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0001-5829-7327
Stavroula Kostaridou NikolopoulouDepartment of Paediatrics, Penteli Children's Hospital, 15236 Athens, Greece.
Panagiotis PlotasDepartment of Cardiology, University of Patras Medical School, 26504 Patras, Greece.
Konstantinos KontoangelosFirst Department of Psychiatry, Eginition Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Ignatios IkonomidisSecond Cardiology Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0001-8241-7886
Nikolaos P E KadoglouMedical School, University of Cyprus, Nicosia 1678, Cyprus.ORCID 0000-0002-7830-3488
Athanasios RaptisSecond Department of Internal Medicine and Research Institute, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Vaia LambadiariSecond Department of Internal Medicine and Research Institute, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
National and Kapodistrian University of Athens · GRPenteli General Children's Hospital · GRUniversity of Cyprus · CYUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: stress hyperglycemia (SH) is a relatively frequent finding in pediatric patients. The purpose of this prospective observational study was to identify the prevalence of pediatric SH and its associated risk factors in Greece. Methods: A total of 1005 patients without diabetes who were admitted consecutively for acute illness in a Pediatric Emergency Department were included in the study. Medical history, anthropometric measurements, blood glucose levels, and the medication administered were recorded. A questionnaire was distributed to parents regarding medical and perinatal history and sociodemographic characteristics. Results: There were 72 cases of SH on admission (7.2%) and 39 (3.9%) during hospitalization. Mean age was 6.4 years; 50.3% were male. SH on admission was associated with oral corticosteroid therapy (21.1% vs. 4.7%, p < 0.001), inhaled corticosteroids (12.7% vs. 3%, p < 0.001), and inhaled β2-agonists (30.6% vs. 10.7%, p < 0.001). In-hospital hyperglycemia was associated with oral corticosteroids (adjusted OR = 3.32), inhaled corticosteroids (OR = 10.03) and inhaled β2-agonists (OR = 5.01). Children with asthma were 5.58 and 7.86 times more likely to present admission and in-hospital hyperglycemia, respectively. Conclusions: This is the first report of SH prevalence in pediatric patients in Greece. Asthma, corticosteroids, and β2-agonists significantly increase the risk of SH. No parental factors seem to predispose to SH.

Indexed as

asthmacorticosteroidspediatricstress hyperglycemiaβ2-agonists

Identifiers

PMID35268392
PMCPMC8911079
OpenAlexW4214702655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.