ArticleJournal of clinical medicine2022
Pulmonary Artery Pulsatility Index and Hemolysis during Impella-Incorporated Mechanical Circulatory Support.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Association of Hemodynamic Parameters with Clinical Outcomes in Cardiogenic Shock: Insights from Full-Flow Micro-Axial Flow Pump Data in a Retrospective Single-Center Study.Journal of clinical medicine · 2026Article
- Short-Term Outcomes of Intra-Aortic Balloon Pump vs. Microaxial Flow Pump for Fulminant Myocarditis Supported by Venoarterial Extracorporeal Membrane Oxygenation.Circulation reports · 2026Article
- Management of Dialysis for Patients Receiving Mechanical Circulatory Support.Journal of the American Society of Nephrology : JASN · 2026Review
- Computational fluid dynamics simulating of the FDA benchmark blood pump with different coefficient sets and scaler shear stress models used in the power-law hemolysis model.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025Article
- Impact of the spleen size on short-term prognosis in patients with cardiogenic shock receiving Impella-incorporated temporary mechanical circulatory support.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025Article
- Evaluation of hemolysis in patients supported with Impella 5.5: a single center experience.Journal of cardiothoracic surgery · 2025Article
- Impact of inhaled nitric oxide therapy in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation combined with Impella: a retrospective cohort study.Journal of intensive care · 2024Article
- Role of Mechanical Circulatory Support in Complex High-Risk and Indicated Percutaneous Coronary Intervention: Current Indications, Device Options, and Potential Complications.Journal of clinical medicine · 2024Review
- Monitoring a Mystery: The Unknown Right Ventricle during Left Ventricular Unloading with Impella in Patients with Cardiogenic Shock.Journal of clinical medicine · 2024Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Impella is a percutaneous transcatheter left ventricular assist device. Device-related hemolysis is a serious complication that is sometimes encountered depending on the device position, device speed, and support duration. However, the impact of hemodynamics on the occurrence of hemolysis remains unknown. In this study, we aimed to clarify the relationships between hemodynamics, especially right ventricular function, and the occurrence of hemolysis during Impella-incorporated mechanical circulatory support. Methods: Consecutive patients who received Impella (2.5, CP, and 5.0) support at our institute between March 2018 and July 2021 were retrospectively included. The relationships between the pulmonary artery pulsatility index (PAPi) immediately after Impella insertion and the occurrence of hemolysis were investigated. Results: Forty-two patients (median 71 years old, 60% men) were included. Hemolysis occurred in 20 patients (48%). A cutoff of PAPi to predict hemolysis was calculated as 1.3, with 80.0% sensitivity and 72.7% specificity. Lower PAPi (<1.3) significantly correlated with the occurrence of hemolysis with an odds ratio of 11.65 (95% confidence interval 1.58−85.98, p = 0.017), adjusted for other potential confounders. Survival discharge was significantly lower in patients with lower PAPi (<1.3) (50% vs. 86%, p = 0.019). Conclusions: The results of this study suggest that patients with right ventricular impairment indicated by lower PAPi following the initiation of Impella-incorporated mechanical circulatory support have a higher risk of hemolysis.
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