Evidence map›Paper›PMID 35268099›Full record

Trial reportNutrients2022

The Effect of Oral Probiotics (Streptococcus Salivarius k12) on the Salivary Level of Secretory Immunoglobulin A, Salivation Rate, and Oral Biofilm: A Pilot Randomized Clinical Trial.

Ksenia Babina, Dilara Salikhova, Maria Polyakova, Oxana Svitich, Roman Samoylikov, Samya Ahmad El-Abed, Alexandr Zaytsev, Nina Novozhilova

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05727436 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Oral Probiotics Containing Streptococcus Salivarius M18 on Gingivitis and Oral Hygiene: A Randomized Clinical Trial

TypeinterventionalSponsorI.M. Sechenov First Moscow State Medical UniversityRan2023 to 2023Enrolled61ConditionsGingivitis, ChronicArmsDentoblis, Placebo
NCT05919134 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effect of Oral Probiotics Containing Streptococcus Salivarius M18 on Gingivitis and Oral Hygiene: a Randomized Clinical Trial: Part 2

TypeinterventionalSponsorI.M. Sechenov First Moscow State Medical UniversityRan2023 to 2023Enrolled60ConditionsGingivitis, ChronicArmsDentoblis, Placebo
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Use ofFrontiers in immunology · 2023
    Trial
  3. Review
  4. Article
  5. Journal of oral microbiology · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Efficacy ofMicroorganisms · 2024
    Article
  12. A Three-Month Probiotic (theDentistry journal · 2024
    Article
  13. Article
  14. Article
  15. Antimicrobial effect of probiotic bacteriocins onJournal of oral microbiology · 2024
    Article
  16. Evaluation of the effects ofDental research journal · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ksenia BabinaDepartment of Therapeutic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.ORCID 0000-0003-4445-0858
Dilara SalikhovaDepartment of Therapeutic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.ORCID 0000-0001-8008-4977
Maria PolyakovaDepartment of Therapeutic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Oxana SvitichDepartment of Microbiology, Virology, and Immunology, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Roman SamoylikovI.I. Mechnikov Research Institute of Vaccines and Sera, 105064 Moscow, Russia.
Samya Ahmad El-AbedI.I. Mechnikov Research Institute of Vaccines and Sera, 105064 Moscow, Russia.
Alexandr ZaytsevInstitute of Linguistics and Intercultural Communication, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
Nina NovozhilovaDepartment of Therapeutic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.ORCID 0000-0002-1073-7693
Sechenov University · RUResearch Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to assess the effect of oral probiotics containing the

Indexed as

ProbioticsStreptococcus salivariusBiofilmsHumansImmunoglobulin A, SecretoryPilot ProjectsSalivaSalivationImmunoglobulin A, Secretorydental biofilmprobioticssalivary secretory immunoglobulins AStreptococcus salivarius K12unstimulated salivary flow rate

Identifiers

PMID35268099
PMCPMC8912462
OpenAlexW4221095342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.