Evidence map›Paper›PMID 35268027›Full record

Trial reportNutrients2022

Incremental Doses of Nitrate-Rich Beetroot Juice Do Not Modify Cognitive Function and Cerebral Blood Flow in Overweight and Obese Older Adults: A 13-Week Pilot Randomised Clinical Trial.

Abrar M Babateen, Oliver M Shannon, Gerard M O'Brien, Edward Okello, Ellen Smith, Dilara Olgacer, Christina Koehl, William Fostier, Emma Wightman, David Kennedy and 2 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06151015 (Testing the Combined Effect of Dietary Nitrate and Caloric Restriction on Cognitive and Vascular Function in Older Adults Living with Overweight or Obesity), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06151015 narecruitingnot on this mapstarted 2024, after this paper: background citation

Testing the Combined Effect of Dietary Nitrate and Caloric Restriction on Cognitive and Vascular Function in Older Adults Living with Overweight or Obesity: a 28-Day Pilot Randomised Trial

TypeinterventionalSponsorMoira TaylorRan2024 to 2025Enrolled20ConditionsHealthy, Older Adults, Overweight and ObesityArmsNitrate-rich beetroot juice plus calorie-restricted diet, Nitrate-rich beetroot juice plus weight-maintenance diet
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Abrar M BabateenHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Oliver M ShannonHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Gerard M O'BrienHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Edward OkelloHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.ORCID 0000-0002-5741-666X
Ellen SmithBrain Performance and Nutrition Research Centre, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
Dilara OlgacerHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Christina KoehlHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
William FostierHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.ORCID 0000-0003-3564-4933
Emma WightmanBrain Performance and Nutrition Research Centre, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
David KennedyBrain Performance and Nutrition Research Centre, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
John C MathersHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.ORCID 0000-0003-3406-3002
Mario SiervoHuman Nutrition Research Centre, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Newcastle University · GBNorthumbria University · GBUmm al-Qura University · SAUniversity of Nottingham · GB

Funding

Medical Research Council G0700718
6 · The paper itself

Abstract

Nitrate-rich food increases nitric oxide (NO) production and may have beneficial effects on vascular, metabolic, and brain function. This pilot study tested the effects of prolonged consumption of a range of doses of dietary nitrate (NO

Indexed as

Beta vulgarisNitratesAgedCerebrovascular CirculationCognitionHumansMiddle AgedObesityOverweightPilot ProjectsSingle-Blind MethodNitratesbeetroot juicecerebral blood flowcognitioninorganic nitrateolder adults

Identifiers

PMID35268027
PMCPMC8912345
OpenAlexW4214938546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.