ArticleNutrients2022
Chicory: Understanding the Effects and Effectors of This Functional Food.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Pooled it
- Chicory Extract Alleviates Anthracycline-Induced Cardiotoxicity by Inhibiting Mitochondrial Damage via the UCP2/NLRP3 Pathway.International journal of molecular sciences · 2026Article
- Root metabolite profiles support a chemical-trophic filtering hypothesis for genotype- and stage-specific rhizosphere assembly in chicory.Frontiers in microbiology · 2026Article
- Plant Metabolome Between Root and Aerial Parts ofMetabolites · 2025Article
- Evaluating the effect of chicory on serum ferritin levels in transfusion-dependent Β-thalassemia patients: a randomized clinical trial.Annals of medicine and surgery (2012) · 2025Article
- Coffee and chicory blend: properties, nutrition, and health implications.Journal of food science and technology · 2025Review
- Balancing the Oral Redox State: Endogenous and Exogenous Sources of Reactive Oxygen Species and the Antioxidant Role of Lamiaceae and Asteraceae.Dentistry journal · 2025Review
- Article
- Unveiling the hidden allies of industrial chicory-a metagenomic exploration of rhizosphere microbiota and their impact on productivity and plant health.Frontiers in microbiology · 2025Article
- Bitter Perception and Effects of Foods Rich in Bitter Compounds on Human Health: A Comprehensive Review.Foods (Basel, Switzerland) · 2024Review
- Article
- Assessment of safety and in situ antibacterial activity of Weissella cibaria strains isolated from dairy farms in Minas Gerais State, Brazil, for their food application.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Supplementation with Complex Dietary Fiber during Late Pregnancy and Lactation Can Improve Progeny Growth Performance by Regulating Maternal Antioxidant Status and Milk Quality.Antioxidants (Basel, Switzerland) · 2023Article
- Phytobiotic-Prebiotic Feed Additive Containing a Combination of Carob Pulp, Chicory, and Fenugreek Improve Growth Performance, Carcass Traits, and Fecal Microbiota of Fattening Pigs.Animals : an open access journal from MDPI · 2023Article
- Modulation of Hepatic Functions by Chicory (Pharmaceuticals (Basel, Switzerland) · 2023Article
- Health Benefits of Key Constituents inNutrients · 2023Review
- Re-Visiting Antioxidant Therapy in Murine Advanced Atherosclerosis with Brussels Chicory, a Typical Vegetable in Mediterranean Diets.Nutrients · 2023Article
- Dietary Inclusion of Dried Chicory Root Affects Cecal Mucosa Proteome of Nursery Pigs.Animals : an open access journal from MDPI · 2022Article
- Dietary Polyphenol, Gut Microbiota, and Health Benefits.Antioxidants (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 3 institutions in 2 countries.
Funding
Abstract
Industrial chicory has been the subject of numerous studies, most of which provide clinical observations on its health effects. Whether it is the roasted root, the flour obtained from the roots or the different classes of molecules that enter into the composition of this plant, understanding the molecular mechanisms of action on the human organism remains incomplete. In this study, we were interested in three molecules or classes of molecules present in chicory root: fructose, chlorogenic acids, and sesquiterpene lactones. We conducted experiments on the murine model and performed a nutrigenomic analysis, a metabolic hormone assay and a gut microbiota analysis, associated with in vitro observations for different responses. We have highlighted a large number of effects of all these classes of molecules that suggest a pro-apoptotic activity, an anti-inflammatory, antimicrobial, antioxidant, hypolipidemic and hypoglycemic effect and also an important role in appetite regulation. A significant prebiotic activity was also identified. Fructose seems to be the most involved in these activities, contributing to approximately 83% of recorded responses, but the other classes of tested molecules have shown a specific role for these different effects, with an estimated contribution of 23-24%.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.