Evidence map›Paper›PMID 35267922›Full record

ReviewNutrients2022

Protein Quality in Perspective: A Review of Protein Quality Metrics and Their Applications.

Shiksha Adhikari, Marijke Schop, Imke J M de Boer, Thom Huppertz

Abstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

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  4. Transcriptome Analysis Reveals a Potential Response Mechanism ofJournal of fungi (Basel, Switzerland) · 2026
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shiksha AdhikariFood Quality & Design Group, Wageningen University & Research, 6708 WG Wageningen, The Netherlands.ORCID 0000-0002-5780-3563
Marijke SchopAnimal Production Systems Group, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.
Imke J M de BoerAnimal Production Systems Group, Wageningen University & Research, 6708 WD Wageningen, The Netherlands.
Thom HuppertzFood Quality & Design Group, Wageningen University & Research, 6708 WG Wageningen, The Netherlands.ORCID 0000-0003-4142-9359

Funding

Dutch Dairy Association n.a.
6 · The paper itself

Abstract

For design of healthy and sustainable diets and food systems, it is important to consider not only the quantity but also the quality of nutrients. This is particularly important for proteins, given the large variability in amino acid composition and digestibility between dietary proteins. This article reviews measurements and metrics in relation to protein quality, but also their application. Protein quality methods based on concentrations and digestibility of individual amino acids are preferred, because they do not only allow ranking of proteins, but also assessment of complementarity of protein sources, although this should be considered only at a meal level and not a diet level. Measurements based on ileal digestibility are preferred over those on faecal digestibility to overcome the risk of overestimation of protein quality. Integration of protein quality on a dietary level should also be done based on measurements on an individual amino acid basis. Effects of processing, which is applied to all foods, should be considered as it can also affect protein quality through effects on digestibility and amino acid modification. Overall, protein quality data are crucial for integration into healthy and sustainable diets, but care is needed in data selection, interpretation and integration.

Indexed as

DigestionAmino AcidsDietary ProteinsIleumAmino AcidsDietary Proteinscomplementaritydigestibilityfood processingindispensable amino acidsprotein quality

Identifiers

PMID35267922
PMCPMC8912699

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.