Evidence map›Paper›PMID 35267910›Full record

ArticleNutrients2022

Anthropometric Measures and Risk of Rheumatoid Arthritis in the French E3N Cohort Study.

Carine Salliot, Yann Nguyen, Xavier Mariette, Marie-Christine Boutron-Ruault, Raphaèle Seror

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carine SalliotCentre for Research in Epidemiology and Population Health (CESP), INSERM U1018, Paris-Saclay University, 94800 Villejuif, France.ORCID 0000-0003-1066-4161
Yann NguyenCentre for Research in Epidemiology and Population Health (CESP), INSERM U1018, Paris-Saclay University, 94800 Villejuif, France.ORCID 0000-0002-0866-3824
Xavier MarietteCentre of Immunology of Viral Infections and Auto-Immune Diseases (IMVA), INSERM U1184, Paris-Saclay University, 94270 Le Kremlin Bicêtre, France.
Marie-Christine Boutron-RuaultCentre for Research in Epidemiology and Population Health (CESP), INSERM U1018, Paris-Saclay University, 94800 Villejuif, France.
Raphaèle SerorCentre of Immunology of Viral Infections and Auto-Immune Diseases (IMVA), INSERM U1184, Paris-Saclay University, 94270 Le Kremlin Bicêtre, France.
Inserm · FR

Funding

Agence Nationale de la Recherche ANR-10-COHO-0006
6 · The paper itself

Abstract

We aimed to assess the relationships between anthropometric measures and risk of rheumatoid arthritis (RA). The E3N cohort included 98,995 women (aged 40−65 years at the recruitment) who completed mailed questionnaires on reproductive factors, lifestyle, and health-related information, including anthropometric measures, every 2−3 years. Cox proportional hazards regression models with age as the time scale and adjusted on known RA risk factors were used to estimate hazard ratios (HRs) and 95% confidence intervals for the risk of incident RA in the overall population (n = 78,452) and after stratification on smoking exposure. Incident RA diagnosis was validated in 698 women. Abdominal obesity (waist circumference >88 cm) was associated with RA (HR = 1.2 (1.0−1.5)), independent of BMI; whereas obesity, defined as BMI ≥ 30 kg/m2, was marginally associated with RA (HR = 1.26 (0.9−1.5), ptrend = 0.0559). Taking lean body shape (BS) as reference, medium BS at puberty (HR = 1.3 (1.0−1.7)) and medium-large BS at perimenopausal period (HR = 1.5 (1.1−1.9)) were associated with the risk of RA among never-smoker women, independent of BMI. Regarding BS trajectory, taking constantly lean BS as reference, constantly large BS from puberty to perimenopause was associated with RA among non-smokers (HR = 2.10 (1.2−3.6)), independent of BMI.

Indexed as

Arthritis, RheumatoidWhite PeopleAdultAgedBody Mass IndexCohort StudiesFemaleHumansMiddle AgedWaist Circumferenceanthropometric measuresbody shape trajectoriesprospective cohortrheumatoid arthritisrisk factor

Identifiers

PMID35267910
PMCPMC8912452
OpenAlexW4213458088

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.