Evidence map›Paper›PMID 35267692›Full record

ArticlePolymers2022

Single-Chain Mechanical Properties of Gelatin: A Single-Molecule Study.

Lu Qian, Kai Zhang, Xin Guo, Junyu Zhou, Miao Yu

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lu QianSchool of Materials Science and Engineering, South China University of Technology, Guangzhou 510000, China.
Kai ZhangSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Xin GuoSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, China.ORCID 0000-0001-8494-4516
Junyu ZhouSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Miao YuSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, China.ORCID 0000-0002-0493-7277
Sichuan University · CNSouth China University of Technology · CN

Funding

China Postdoctoral Science Foundation 2020TQ0103City-University Research Fund 2020CDYB-12City-University Research Fund 2021CDLZ-2City-University Research Fund 2021CDSN-17City-University Research Fund 2021CDZG-8
6 · The paper itself

Abstract

Gelatin is an important natural biological resource with a wide range of applications in the pharmaceutical, industrial and food industries. We investigated the single-chain behaviors of gelatin by atomic force microscopy (AFM)-based single-molecule force spectroscopy (SMFS), and found that gelatin exists as long chains by fitting with the M-FJC model. By comparing the single-chain elasticity in a nonpolar organic solvent (nonane) and DI water, it was surprising to find that there was almost no difference in the single-chain elasticity of gelatin in nonane and DI water. Considering the specificity of gelatin solubility and the solvent size effect of nonane molecules, when a single gelatin chain is pulled into loose nonane, dehydration does not occur due to strong binding water interactions. Gelatin chains can only interact with water molecules at high temperatures; therefore, no further interaction of single gelatin chains with water molecules occurred at the experimental temperature. This eventually led to almost no difference in the single-chain F-E curves under the two conditions. It is expected that our study will enable the deep exploration of the interaction between water molecules and gelatin and provide a theoretical basis and experimental foundation for the design of gelatin-based materials with more functionalities.

Indexed as

binding watergelatinsingle-chain elasticitysingle-molecule force spectroscopy

Identifiers

PMID35267692
PMCPMC8912665
OpenAlexW4213422950

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.