Evidence map›Paper›PMID 35267583›Full record

ArticleCancers2022

Level II Oncoplastic Surgery as an Alternative Option to Mastectomy with Immediate Breast Reconstruction in the Neoadjuvant Setting: A Multidisciplinary Single Center Experience.

Alba Di Leone, Antonio Franco, Daniela Andreina Terribile, Stefano Magno, Alessandra Fabi, Alejandro Martin Sanchez, Sabatino D'Archi, Lorenzo Scardina, Maria Natale, Elena Jane Mason and 11 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Alba Di LeoneBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0002-8219-5336
Antonio FrancoBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Daniela Andreina TerribileBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Stefano MagnoBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0002-3721-9693
Alessandra FabiPrecision Medicine Breast Unit, Scientific Directorate, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0002-6320-2609
Alejandro Martin SanchezBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Sabatino D'ArchiBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Lorenzo ScardinaBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0002-5828-2851
Maria NataleBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0001-5778-8941
Elena Jane MasonBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0003-0152-049X
Federica MurandoBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Fabio MarazziCancer Radiation Therapy, Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Armando OrlandiMedical Oncology, Department of Medical and Surgical Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0001-5253-4678
Ida ParisCancer Gynaecology, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0002-7445-3366
Giuseppe ViscontiPlastic Surgery, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Antonella PalazzoMedical Oncology, Department of Medical and Surgical Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Valeria MasielloCancer Radiation Therapy, Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0001-7589-7623
Liliana Barone AdesiPlastic Surgery, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Marzia SalgarelloPlastic Surgery, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Riccardo MasettiBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.
Gianluca FranceschiniBreast Unit, Department of Women, Children and Public Health Sciences, "A. Gemelli" IRCCS, 00168 Roma, Italy.ORCID 0000-0002-2950-3395

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncoplastic surgery level II techniques (OPSII) are used in patients with operable breast cancer. There is no evidence regarding their safety and efficacy after neoadjuvant chemotherapy (NAC). The aim of this study was to compare the oncological and aesthetic outcomes of this technique compared with those observed in mastectomy with immediate breast reconstruction (MIBR), in post-NAC patients undergoing surgery between January 2016 and March 2021. Local disease-free survival (L-DFS), regional disease-free survival (R-DFS), distant disease-free survival (D-DFS), and overall survival (OS) were compared; the aesthetic results and quality of life (QoL) were evaluated using BREAST-Q. A total of 297 patients were included, 87 of whom underwent OPSII and 210 of whom underwent MIBR. After a median follow-up of 39.5 months, local recurrence had occurred in 3 patients in the OPSII group (3.4%), and in 13 patients in the MIBR group (6.1%) (

Indexed as

aesthetic and oncological outcomesbreast cancerimmediate breast reconstructionmastectomyneoadjuvant chemotherapyoncoplastic surgeryquality of life

Identifiers

PMID35267583
PMCPMC8909600

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.