Evidence map›Paper›PMID 35267573›Full record

ArticleCancers2022

The Effect of Hypoxia on Relative Biological Effectiveness and Oxygen Enhancement Ratio for Cells Irradiated with Grenz Rays.

Chun-Chieh Chan, Fang-Hsin Chen, Kuang-Lung Hsueh, Ya-Yun Hsiao

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chun-Chieh ChanDepartment of Computer Science and Information Engineering, National Formosa University, Yunlin 632301, Taiwan.ORCID 0000-0002-1156-9791
Fang-Hsin ChenDepartment of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-1671-4863
Kuang-Lung HsuehInstitute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.
Ya-Yun HsiaoDepartment of Radiology, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.ORCID 0000-0001-7494-8767

Funding

Chung Shan Medical University, Taichung, Taiwan CSMU-INT-110-12Linkou-Chang Gung Memorial Hospital, Taoyuan, Taiwan CMRPD1H0473Linkou-Chang Gung Memorial Hospital, Taoyuan, Taiwan CMRPD1J0322Ministry of Sciences and Technology, Taiwan MOST 109-2314-B-182-078-MY3Ministry of Sciences and Technology, Taiwan MOST 110-2628-B-182-008
6 · The paper itself

Abstract

Grenz-ray therapy (GT) is commonly used for dermatological radiotherapy and has a higher linear energy transfer, relative biological effectiveness (RBE) and oxygen enhancement ratio (OER). GT is a treatment option for lentigo maligna and lentigo maligna melanoma. This study aims to calculate the RBE for DNA double-strand break (DSB) induction and cell survival under hypoxic conditions for GT. The yield of DSBs induced by GT is calculated at the aerobic and hypoxic conditions, using a Monte Carlo damage simulation (MCDS) software. The RBE value for cell survival is calculated using the repair-misrepair-fixation (RMF) model. The RBE values for cell survival for cells irradiated by 15 kV, 10 kV and 10 kVp and titanium K-shell X-rays (4.55 kV) relative to

Indexed as

cell survivaldouble strand breakGrenz rayshypoxiaoxygen enhancement ratiorelative biological effectiveness

Identifiers

PMID35267573
PMCPMC8909589

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.