Evidence map›Paper›PMID 35267541›Full record

ArticleCancers2022

Role of the Skin Microenvironment in Melanomagenesis: Epidermal Keratinocytes and Dermal Fibroblasts Promote BRAF Oncogene-Induced Senescence Escape in Melanocytes.

Shreyans Sadangi, Katarina Milosavljevic, Edgardo Castro-Perez, Marcos Lares, Mithalesh Singh, Sarah Altameemi, David J Beebe, Jose M Ayuso, Vijayasaradhi Setaluri

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Advances in Microengineered Platforms for Skin Research.JID innovations : skin science from molecules to population health · 2025
    Review
  2. Review
  3. Dangerous liaisons: Loss of keratinocyte control over melanocytes in melanomagenesis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2024
    Review
  4. Contribution of Keratinocytes in Skin Cancer Initiation and Progression.International journal of molecular sciences · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review: The Key Factors to Melanomagenesis.Life (Basel, Switzerland) · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shreyans SadangiDepartment of Dermatology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Katarina MilosavljevicDepartment of Dermatology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Edgardo Castro-PerezDepartment of Dermatology, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0003-4884-9479
Marcos LaresDepartment of Dermatology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Mithalesh SinghDepartment of Dermatology, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-1812-9860
Sarah AltameemiDepartment of Dermatology, University of Wisconsin-Madison, Madison, WI 53705, USA.
David J BeebeDepartment of Pathology and Laboratory Medicine, University of Wisconsin, 1111 Highland Ave., Madison, WI 53705, USA.
Jose M AyusoDepartment of Dermatology, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-9414-1845
Vijayasaradhi SetaluriDepartment of Dermatology, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0001-6468-7663
University of Wisconsin–Madison · US

Funding

Radiation response within the tumor microenvironmentR01CA164492 · NCI · UNIVERSITY OF CHICAGO · PI KRON, STEPHEN J. · 2011 to 2015
$4.8M
Skin Diseases Research Center at the University of WisconsinP30AR066524 · NIAMS · UNIVERSITY OF WISCONSIN-MADISON · PI LONGLEY, B JACK · 2014 to 2018
$2.6M
(PQ7) Quantitative in vivo optical imaging of tumor heterogeneityR01CA205101 · NCI · MORGRIDGE INSTITUTE FOR RESEARCH, INC. · PI SKALA, MELISSA CAROLINE · 2016 to 2020
$1.9M
Cellular-level Optical Metabolic Imaging to Predict Drug Response in CancerR01CA185747 · NCI · VANDERBILT UNIVERSITY · PI SKALA, MELISSA CAROLINE · 2014 to 2019
$1.6M
National Science Foundation CBET-1642287NCI NIH HHS R01 CA164492NCI NIH HHS R01 CA185747NCI NIH HHS R01 CA205101NIAMS NIH HHS P30 AR066524NIAMS NIH HHS P30AR066524NIH HHS R01 CA164492NIH HHS R01 CA185747NIH HHS R01 CA205101United States Department of Defense W81XWH-18-PRCRP-IASF
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

melanomamicrofluidicssenescencetumor microenvironment

Identifiers

PMID35267541
PMCPMC8909265
OpenAlexW4214487467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.