Evidence map›Paper›PMID 35267486›Full record

ArticleCancers2022

Present Practice of Radiative Deep Hyperthermia in Combination with Radiotherapy in Switzerland.

Emanuel Stutz, Emsad Puric, Adela Ademaj, Arnaud Künzi, Reinhardt Krcek, Olaf Timm, Dietmar Marder, Markus Notter, Susanne Rogers, Stephan Bodis and 1 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emanuel StutzDepartment of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Emsad PuricDepartment of Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001 Aarau, Switzerland.
Adela AdemajDepartment of Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001 Aarau, Switzerland.ORCID 0000-0001-6568-7198
Arnaud KünziClinical Trials Unit, University of Bern, 3010 Bern, Switzerland.
Reinhardt KrcekDepartment of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Olaf TimmDepartment of Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001 Aarau, Switzerland.
Dietmar MarderDepartment of Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001 Aarau, Switzerland.ORCID 0000-0003-0865-9283
Markus NotterRadiation Oncology, Lindenhofspital Bern, 3012 Bern, Switzerland.ORCID 0000-0002-6084-8340
Susanne RogersDepartment of Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001 Aarau, Switzerland.ORCID 0000-0003-0094-1890
Stephan BodisDepartment of Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001 Aarau, Switzerland.
Oliver RiestererDepartment of Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001 Aarau, Switzerland.ORCID 0000-0002-9508-0546

Funding

Marie Skłodowska-Curie (MSCA-ITN) grant 955625Scientific Association of Swiss Radiation Oncology (SASRO) research grant 0
6 · The paper itself

Abstract

backgroundModerate hyperthermia is a potent and evidence-based radiosensitizer. Several indications are reimbursed for the combination of deep hyperthermia with radiotherapy (dHT+RT). We evaluated the current practice of dHT+RT in Switzerland.

methodsAll indications presented to the national hyperthermia tumor board for dHT between January 2017 and June 2021 were evaluated and treatment schedules were analyzed using descriptive statistics.

resultsOf 183 patients presented at the hyperthermia tumor board, 71.6% were accepted and 54.1% (99/183) finally received dHT. The most commonly reimbursed dHT indications were "local recurrence and compression" (20%), rectal (14.7%) and bladder (13.7%) cancer, respectively. For 25.3% of patients, an individual request for insurance cover was necessary. 47.4% of patients were treated with curative intent; 36.8% were in-house patients and 63.2% were referred from other hospitals.

conclusionsApproximately two thirds of patients were referred for dHT+RT from external hospitals, indicating a general demand for dHT in Switzerland. The patterns of care were diverse with respect to treatment indication. To the best of our knowledge, this study shows for the first time the pattern of care in a national cohort treated with dHT+RT. This insight will serve as the basis for a national strategy to evaluate and expand the evidence for dHT.

Indexed as

deep hyperthermiamoderate hyperthermiapatterns of careradiative hyperthermiaradiotherapyreimbursement

Identifiers

PMID35267486
PMCPMC8909523

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.