ReviewCancers2022
Patient Preferences for Treatment Outcomes in Oncology with a Focus on the Older Patient-A Systematic Review.
Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Treatment decision-making and quality of life versus length of life preferences of older patients with early stage cancer: A systematic review.Journal of geriatric oncology · 2025Pooled it
- Management of immune checkpoint inhibitor-associated toxicities in older adults with cancer: recommendations from the International Society of Geriatric Oncology (SIOG).The Lancet. Oncology · 2025Guideline
- Patient and oncologist expectations of functional prognosis among older adults with acute myeloid leukemia.Blood advances · 2026Trial
- Fatigue, physical function, and the context of social vulnerability for older adults with cancer.Journal of geriatric oncology · 2025Trial
- Trial
- Geriatric assessment with management for older patients with cancer receiving radiotherapy: a cluster-randomised controlled pilot study.BMC medicine · 2024Trial
- Outcomes That Matter in Gastrointestinal Cancer Care: A Focus Group Study of Patient-Centred Outcomes Identified by Patients and Care Partners.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Patient perspectives on single-port versus multi-port robotic-assisted urologic oncology procedures: a survey-based analysis.Journal of robotic surgery · 2026Article
- The correlation between pain and function in cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Personalizing cancer care for older adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Patient-centered valuation of minimally invasive surgery in cervical cancer: a discrete choice experiment.Journal of gynecologic oncology · 2026Article
- Perceptions of the Values and Outcomes to Improve Cancer Experiences (VOICE) tool: a digital values-clarification instrument and tailored summary report for older adults with advanced cancer.Journal of patient-reported outcomes · 2026Article
- How to Analyze Longitudinal Patient-Reported Outcomes in Populations With High Mortality Rates.Journal of the American Geriatrics Society · 2026Article
- Self-reported health, function, and use of health care services in older prostate cancer survivors compared to matched controls: a cross-sectional study.Journal of cancer survivorship : research and practice · 2026Article
- The ESMO/SIOG Cancer in the Elderly Working Group pragmatic strategies for clinical trial designs and endpoints in older adults with cancer.ESMO open · 2026Review
- Registry-based randomised phase II study of Enzalutamide versus Abiraterone: assessing cognitive function in eLderly patients with metastatic castration-resistant Prostate cancer (REAL-Pro).ESMO real world data and digital oncology · 2026Article
- Patient and Clinician Views on Risk Prediction for Chemotherapy-Induced Peripheral Neuropathy.Journal of pain & palliative care pharmacotherapy · 2026Article
- Healthcare Workers' Views on Approaches to Discussing Alternative Treatment Options in Multidisciplinary Cancer Care.Cureus · 2026Article
- Advancing personalised oncologic care for older adults with head and neck cancer through structured international collaboration.Frontiers in oncology · 2026Article
- Patient preferences for attributes of bispecific antibodies for relapse/refractory diffuse large B-cell lymphoma in the US.Future oncology (London, England) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
For physicians, it is important to know which treatment outcomes are prioritized overall by older patients with cancer, since this will help them to tailor the amount of information and treatment recommendations. Older patients might prioritize other outcomes than younger patients. Our objective is to summarize which outcomes matter most to older patients with cancer. A systematic review was conducted, in which we searched Embase and Medline on 22 December 2020. Studies were eligible if they reported some form of prioritization of outcome categories relative to each other in patients with all types of cancer and if they included at least three outcome categories. Subsequently, for each study, the highest or second-highest outcome category was identified and presented in relation to the number of studies that included that outcome category. An adapted Newcastle-Ottawa Scale was used to assess the risk of bias. In total, 4374 patients were asked for their priorities in 28 studies that were included. Only six of these studies had a population with a median age above 70. Of all the studies, 79% identified quality of life as the highest or second-highest priority, followed by overall survival (67%), progression- and disease-free survival (56%), absence of severe or persistent treatment side effects (54%), and treatment response (50%). Absence of transient short-term side effects was prioritized in 16%. The studies were heterogeneous considering age, cancer type, and treatment settings. Overall, quality of life, overall survival, progression- and disease-free survival, and severe and persistent side effects of treatment are the outcomes that receive the highest priority on a group level when patients with cancer need to make trade-offs in oncologic treatment decisions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.