Evidence map›Paper›PMID 35267433›Full record

ReviewCancers2022

Precision Oncology in Lower-Grade Gliomas: Promises and Pitfalls of Therapeutic Strategies Targeting IDH-Mutations.

Pasquale Persico, Elena Lorenzi, Agnese Losurdo, Angelo Dipasquale, Antonio Di Muzio, Pierina Navarria, Federico Pessina, Letterio Salvatore Politi, Giuseppe Lombardi, Armando Santoro and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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  13. The Significance ofInternational journal of molecular sciences · 2022
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Pasquale PersicoDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Milan, Italy.ORCID 0000-0003-2446-8604
Elena LorenziOncology Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Milan, Italy.
Agnese LosurdoOncology Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Milan, Italy.
Angelo DipasqualeDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Milan, Italy.ORCID 0000-0002-3326-8156
Antonio Di MuzioDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Milan, Italy.
Pierina NavarriaRadiotherapy Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Milan, Italy.ORCID 0000-0002-6913-1442
Federico PessinaDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Milan, Italy.
Letterio Salvatore PolitiDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Milan, Italy.ORCID 0000-0002-6190-6688
Giuseppe LombardiDepartment of Oncology, Oncology 1, Veneto Institute of Oncology IOV-IRCCS, Via Gattamelata 64, 35128 Padua, Italy.ORCID 0000-0003-1316-2132
Armando SantoroDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Milan, Italy.
Matteo SimonelliDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090 Milan, Italy.ORCID 0000-0002-5264-1251
Humanitas University · ITIRCCS Humanitas Research Hospital · ITIstituto Oncologico Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in isocitrate dehydrogenase (

Indexed as

clinical trialsGlioblastomaIDH inhibitorsisocitrate dehydrogenase (IDH) mutationslower-grade gliomasprecision oncologytargeted therapyvaccines

Identifiers

PMID35267433
PMCPMC8909346
OpenAlexW4213443321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.