Evidence map›Paper›PMID 35267228›Full record

ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2022

Left ventricular septal pacing versus left bundle branch pacing in the treatment of atrioventricular block.

Yu Zhou, Jinfeng Wang, Youquan Wei, Wenbo Zhang, Yuwen Yang, Shibao Rui, Changlin Ju

Registry-linked trialAbstract read
In one paragraph

Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06540521 (Intracardiac Electrical Characteristics of LBBAP), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06540521 recruitingnot on this mapstarted 2024, after this paper: background citation

Intracardiac Electrical Characteristics of LBBAP

TypeobservationalSponsorMedtronic Cardiac Rhythm and Heart FailureRan2024 to 2026Enrolled75ConditionsHeart Failure, BradycardiaArmsNo intervention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. An in silico guide for ventriculo-ventricular delay programming for left bundle branch-optimized cardiac resynchronization therapy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Left ventricular septal pacing versus left bundle branch pacing in the treatment of atrioventricular block.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu ZhouDepartment of Emergency, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Jinfeng WangDepartment of Cardiology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Youquan WeiDepartment of Cardiology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Wenbo ZhangDepartment of Cardiology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Yuwen YangDepartment of Cardiology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Shibao RuiDepartment of Cardiology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
Changlin JuDepartment of Cardiology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.ORCID 0000-0001-6035-6154

Funding

Key specialty project of Anhui Province medical and health
6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the feasibility and clinical response of LVSP as an alternative to LBBP.

methodsThis was a retrospective study of pacemaker implantation, and 46 consecutive patients with pacemaker implantation were enrolled in the study. The patients were divided into the LBBP and LVSP groups. Electrocardiogram characteristics, pacing parameters, cardiac function, and safety events were assessed during implantation and 12-month follow-up.

resultsThe procedure time was significantly increased in the LBBP group compared with the LVSP group (53.52 ± 14.39 min vs. 38.13 ± 11.52 min, respectively, p = .000). The pacing QRS duration (PQRSD) decreased by 14.09 ± 41.80 ms in the LBBP group and increased by 9.70 ± 29.60 ms in the LVSP group (p = .031). Furthermore, the left ventricle activation time (LVAT) was shorter in the LBBP group than in the LVSP group (48.70 ± 13.67 ms vs. 58.70 ± 13.67 ms, p =  .032). During the 12-month follow-up, pacing thresholds remained low and stable, and there was no significant decrease in cardiac function. No adverse event was observed during the follow-up period.

conclusionsBoth LBBP and LVSP are safe and feasible methods. LVSP is a good option when multichannel electrophysiological instruments are not available and when the time available for the procedure is limited.

Indexed as

Atrioventricular BlockBundle of HisCardiac Pacing, ArtificialElectrocardiographyHeart VentriclesHumansRetrospective Studiescardiac functionelectrocardiogramleft bundle branch pacingleft ventricular septal pacingphysiological pacing

Identifiers

PMID35267228
PMCPMC9107083

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.