Evidence map›Paper›PMID 35267107›Full record

ArticleAIDS and behavior2022

Predictors of Re-Initiation of Daily Oral Preexposure Prophylaxis Regimen After Discontinuation.

Casey D Xavier Hall, Michael E Newcomb, Christina Dyar, Brian Mustanski

Open access · bronzeAbstract read
In one paragraph

Article in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Casey D Xavier HallDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Michael E NewcombDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Christina DyarCollege of Nursing, Ohio State University, Columbus, OH, USA.
Brian MustanskiDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, United States. brian@northwestern.edu.ORCID http://orcid.org/0000-0001-9222-5116
Northwestern University · USThe Ohio State University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
The RADAR cohort study of multilevel Influences on HIV and substance useU01DA036939 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian Mustanski, Michael E Newcomb · 2014 to 2026
$29.5M
Characterizing PrEP Adherence and Patterns of Use in a Diverse Community Cohort of Young MenR01MD013609 · NIMHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MUSTANSKI, BRIAN, NEWCOMB, MICHAEL E · 2018 to 2021
$1.8M
Understanding Substance Use Risk among Sexual Minority WomenK01DA046716 · NIDA · OHIO STATE UNIVERSITY · PI DYAR, CHRISTINA · 2019 to 2023
$843k
National Center on Minority Health and Health Disparities R01MD013609NCATS NIH HHS UL1 TR001422NIDA NIH HHS K01 DA046716NIDA NIH HHS K01DA046716NIDA NIH HHS U01 DA036939NIDA NIH HHS U01DA036939NIMHD NIH HHS R01 MD013609
6 · The paper itself

Abstract

Daily oral preexposure prophylaxis (PrEP) for reducing HIV transmission is recommended for those at elevated risk, including sexual gender and minorities assigned male at birth (SGM-AMAB). Few studies have examined re-initiation among PrEP discontinuers, which is critical to ensuring optimization of PrEP's protection. The current study examined predictors of re-initiation in a longitudinal sample of SGM-AMAB PrEP discontinuers (n = 253) from 10 waves of an ongoing cohort study (analytic n = 1,129). Multilevel structural equation models were used to examine the effects of psycho-social variables on re-initiation. In adjusted models, health insurance, and partner HIV positive status were significantly positively associated with PrEP re-initation. Being bisexual was significantly negatively associated with re-initiation relative to gay participants. Single status and open relationship agreements were associated with higher odds of re-initiation relative to monogamous relationships. Findings suggest that demographic, partnership characteristics and structural factors influence decisions to re-initiate PrEP after discontinuation.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesAdultBisexualityCohort StudiesFemaleHomosexuality, MaleHumansMaleYoung AdultHIVPre-exposure prophylaxisPrEPRe-initiation

Identifiers

PMID35267107
PMCPMC8907393
OpenAlexW4221044077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.