Evidence map›Paper›PMID 35267104›Full record

ReviewJournal of materials science. Materials in medicine2022

A comprehensive review on methods for promotion of mechanical features and biodegradation rate in amniotic membrane scaffolds.

Raana Sarvari, Peyman Keyhanvar, Samira Agbolaghi, Leila Roshangar, Erfan Bahremani, Neda Keyhanvar, Mehdi Haghdoost, Saeed Heidari Keshel, Afsaneh Taghikhani, Nima Firouzi and 3 more

Abstract readReview
In one paragraph

Review in Journal of materials science. Materials in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  3. Review
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  6. Article
  7. Biomaterials for Corneal Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Raana SarvariStem Cell And Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Peyman KeyhanvarStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Keyhanvarp@tbzmed.ac.ir.ORCID http://orcid.org/0000-0001-8879-1764
Samira AgbolaghiChemical Engineering Department, Faculty of Engineering, Azarbaijan Shahid Madani University, P.O. BOX: 5375171379, Tabriz, Iran.
Leila RoshangarStem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Erfan BahremaniAlavi Ophthalmological Treatment and Educational Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Neda KeyhanvarStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Mehdi HaghdoostDepartment of Infectious Diseases, Tabriz University of Medical Sciences, Tabriz, Iran.
Saeed Heidari KeshelMedical Nanotechnology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Afsaneh TaghikhaniDepartment of Chemistry, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Nima FirouziStem Cell and Tissue Engineering Research Laboratory, Chemical Engineering Faculty, Sahand University of Technology, P.O.BOX:51335-1996, Tabriz, Iran.
Amir ValizadehStem Cell And Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Elham HamediDepartment of Tissue Engineering and Applied Cell Science, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad NouriStem Cell And Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran. Nourimd@tbzmed.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amniotic membrane (AM) is a biological tissue that surrounds the fetus in the mother's womb. It has pluripotent cells, immune modulators, collagen, cytokines with anti-fibrotic and anti-inflammatory effect, matrix proteins, and growth factors. In spite of the biological characteristics, some results have been released in preventing the adhesion on traumatized surfaces. Application of the AM as a scaffold is limited due to its low biomechanical resistance and rapid biodegradation. Therefore, for using the AM during surgery, its modification by different methods such as cross-linking of the membrane collagen is necessary, because the cross-linking is an effective way to reduce the rate of biodegradation of the biological materials. In addition, their cross-linking is likely an efficient way to increase the tensile properties of the material, so that they can be easily handled or sutured. In this regard, various methods related to cross-linking of the AM subsuming the composite materials, physical cross-linking, and chemical cross-linking with the glutraldehyde, carbodiimide, genipin, aluminum sulfate, etc. are reviewed along with its advantages and disadvantages in the current work.

Indexed as

AmnionCarbodiimidesBiocompatible MaterialsCollagenCross-Linking ReagentsTissue EngineeringTissue ScaffoldsBiocompatible MaterialsCarbodiimidesCollagenCross-Linking Reagents

Identifiers

PMID35267104
PMCPMC8913518

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.