Evidence map›Paper›PMID 35266829›Full record

ArticleAntimicrobial agents and chemotherapy2022

Search for a Shared Genetic or Biochemical Basis for Biofilm Tolerance to Antibiotics across Bacterial Species.

Philip S Stewart, Kerry S Williamson, Laura Boegli, Timothy Hamerly, Ben White, Liam Scott, Xiao Hu, Brendan M Mumey, Michael J Franklin, Brian Bothner and 3 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. TheInternational journal of molecular sciences · 2023
    Article
  4. Review
  5. The gene regulatory network ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Philip S StewartCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.ORCID 0000-0001-7773-8570
Kerry S WilliamsonCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Laura BoegliCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Timothy HamerlyCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Ben WhiteCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Liam ScottCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Xiao HuGianforte School of Computing, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Brendan M MumeyGianforte School of Computing, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Michael J FranklinCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Brian BothnerCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.ORCID 0000-0003-1295-9609
Francisco G Vital-LopezDepartment of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Development Command, Fort Detrick, Maryland, USA.
Anders WallqvistDepartment of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Development Command, Fort Detrick, Maryland, USA.ORCID 0000-0002-9775-7469
Garth A JamesCenter for Biofilm Engineering, Montana State Universitygrid.41891.35, Bozeman, Montana, USA.
Montana State University · USHenry M. Jackson Foundation · USTelemedicine & Advanced Technology Research Center · US

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Ultra Performance Liquid Chromatography Tandem Mass Spectrometer for MetabolomicsS10OD028650 · OD · MONTANA STATE UNIVERSITY - BOZEMAN · PI BOTHNER, BRIAN P · 2020 to 2020
$599k
NIGMS NIH HHS P20 GM103474NIH HHS S10 OD028650
6 · The paper itself

Abstract

Is there a universal genetically programmed defense providing tolerance to antibiotics when bacteria grow as biofilms? A comparison between biofilms of three different bacterial species by transcriptomic and metabolomic approaches uncovered no evidence of one. Single-species biofilms of three bacterial species (Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii) were grown

Indexed as

Anti-Bacterial AgentsBiofilmsCarbonPlanktonPseudomonas aeruginosaStaphylococcus aureusAnti-Bacterial AgentsCarbonantibioticbiofilmsmetabolomicphysiologytolerancetranscriptomic

Identifiers

PMID35266829
PMCPMC9017379
OpenAlexW4221085067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.