Evidence map›Paper›PMID 35266816›Full record

ArticlemBio2022

Interleukin-17 Weakens the NAFLD/NASH Process by Facilitating Intestinal Barrier Restoration Depending on the Gut Microbiota.

Shuying He, Shudan Cui, Wen Song, Yonghong Jiang, Hongsheng Chen, Dongjiang Liao, Xinpeng Lu, Jun Li, Xueqing Chen, Liang Peng

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Alteration of small intestinal microbiota in diet-induced steatohepatitis mice.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Food science & nutrition · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shuying HeDepartment of Gastroenterology, First Affiliated Hospital of Guangzhou Medical Universitygrid.470124.4, Guangzhou Medical University, Guangzhou, China.
Shudan CuiShenzhen People's Hospital, Shenzhen, China.
Wen SongSouthern Medical University, Guangzhou, China.
Yonghong JiangDepartment of Gastroenterology, First Affiliated Hospital of Guangzhou Medical Universitygrid.470124.4, Guangzhou Medical University, Guangzhou, China.
Hongsheng ChenState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical Universitygrid.470124.4, Guangzhou Medical University, Guangzhou, China.
Dongjiang LiaoState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical Universitygrid.470124.4, Guangzhou Medical University, Guangzhou, China.
Xinpeng LuState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical Universitygrid.470124.4, Guangzhou Medical University, Guangzhou, China.
Jun LiDepartment of Hepatobiliary Surgery, First Affiliated Hospital of Guangzhou Medical Universitygrid.470124.4, Guangzhou Medical University, Guangzhou, China.
Xueqing ChenDepartment of Gastroenterology, First Affiliated Hospital of Guangzhou Medical Universitygrid.470124.4, Guangzhou Medical University, Guangzhou, China.
Liang PengDepartment of Gastroenterology, First Affiliated Hospital of Guangzhou Medical Universitygrid.470124.4, Guangzhou Medical University, Guangzhou, China.ORCID 0000-0001-7021-4651
First Affiliated Hospital of Guangzhou Medical University · CNShenZhen People’s Hospital · CNSouthern Medical University · CN

Funding

China Postdoctoral Science Foundation 2019M662871China Postdoctoral Science Foundation 2020T130133Fundamental Research Funds for Initial Funding 34001004National Natural Science Foundation of China 81900506National Science Fundation of Guangdong 2018A030313970
6 · The paper itself

Abstract

Interleukin-17 (IL-17) is associated with nonalcoholic fatty liver disease (NAFLD) and gut microbiota, and how IL-17 mediates the NAFLD/nonalcoholic steatohepatitis (NASH) process depending on the gut microbiota is unclear. We found that T helper 17 (T

Indexed as

Gastrointestinal MicrobiomeNon-alcoholic Fatty Liver DiseaseAnimalsDiet, High-FatDysbiosisInterleukin-17MethionineMiceIl17a protein, mouseInterleukin-17Methionineendotoxemiainterleukin-17intestinal barriermicrobiota dysbiosisnonalcoholic steatohepatitis

Identifiers

PMID35266816
PMCPMC9040850
OpenAlexW4220941576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.