Evidence map›Paper›PMID 35266809›Full record

ArticleJournal of feline medicine and surgery2022

Dysbiosis index to evaluate the fecal microbiota in healthy cats and cats with chronic enteropathies.

Chi-Hsuan Sung, Sina Marsilio, Betty Chow, Kailee A Zornow, Jennifer E Slovak, Rachel Pilla, Jonathan A Lidbury, Jörg M Steiner, So Young Park, Min-Pyo Hong and 2 more

Abstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Review
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  10. Oral administration ofJournal of feline medicine and surgery · 2026
    Article
  11. The Effects of DietaryAnimals : an open access journal from MDPI · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Understanding the diversity and roles of the canine gut microbiome.Journal of animal science and biotechnology · 2025
    Review
  18. Feline Coronavirus Prevalence in 493 Cats With Chronic Diarrhea.Journal of veterinary internal medicine · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chi-Hsuan SungGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.ORCID 0000-0003-2588-9697
Sina MarsilioUC Davis School of Veterinary Medicine, Department of Veterinary Medicine and Epidemiology, University of California-Davis, Davis, CA, USA.ORCID 0000-0002-0693-0669
Betty ChowVeterinary Specialty Hospital, San Diego, CA, USA.ORCID 0000-0002-7775-3719
Kailee A ZornowAnimal Medical Center, New York, NY, USA.ORCID 0000-0001-7950-4938
Jennifer E SlovakAnimal Medical Center, New York, NY, USA.ORCID 0000-0001-8516-2380
Rachel PillaGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.ORCID 0000-0001-7758-2609
Jonathan A LidburyGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.
Jörg M SteinerGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.ORCID 0000-0003-3336-2086
So Young ParkGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.
Min-Pyo HongGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.
Steve L HillVeterinary Specialty Hospital, San Diego, CA, USA.
Jan S SuchodolskiGastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPrevious studies have identified various bacterial taxa that are altered in cats with chronic enteropathies (CE) vs healthy cats. Therefore, the aim of this study was to develop a targeted quantitative molecular method to evaluate the fecal microbiota of cats.

methodsFecal samples from 80 client-owned healthy cats and 68 cats with CE were retrospectively evaluated. A panel of quantitative PCR (qPCR) assays was used to measure the fecal abundance of total bacteria and seven bacterial taxa:

resultsThe abundances of total bacteria, CONCLUSIONS AND RELEVANCE: A qPCR-based DI for assessing the fecal microbiota of cats was established. The results showed that a large proportion of cats with CE had an altered fecal microbiota as evidenced by an increased DI. Prospective studies are warranted to evaluate the utility of this assay for clinical assessment of feline CE.

Indexed as

Cat DiseasesInflammatory Bowel DiseasesMicrobiotaAnimalsBacteriaCatsDysbiosisEscherichia coliFecesRetrospective Studieschronic inflammatory enteropathyInflammatory bowel diseasemicrobiomesmall cell lymphoma

Identifiers

PMID35266809
PMCPMC9160961

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.