Evidence map›Paper›PMID 35266805›Full record

ArticleJournal of virology2022

Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order:

Wenhua Kuang, Huanyu Zhang, Yan Cai, Guilin Zhang, Fei Deng, Hailong Li, Yiwu Zhou, Manli Wang, Peng Gong, Yu Guo and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Pharmacophores of Influenza Virus PA Endonuclease Inhibitors.Advances in experimental medicine and biology · 2026
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Wenhua KuangDepartment of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Huanyu ZhangState Key Laboratory of Virology, Wuhan Institute of Virology Chinese Academy of Sciences, Wuhan, Hubei, China.
Yan CaiState Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, China.
Guilin ZhangCenter for Disease Control and Prevention of Xinjiang Military Command, Urumqi, Xinjiang, China.
Fei DengState Key Laboratory of Virology, Wuhan Institute of Virology Chinese Academy of Sciences, Wuhan, Hubei, China.ORCID 0000-0002-5385-083X
Hailong LiCenter for Disease Control and Prevention of Xinjiang Military Command, Urumqi, Xinjiang, China.
Yiwu ZhouDepartment of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Manli WangState Key Laboratory of Virology, Wuhan Institute of Virology Chinese Academy of Sciences, Wuhan, Hubei, China.
Peng GongKey Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.ORCID 0000-0002-8264-7523
Yu GuoState Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, China.ORCID 0000-0002-8109-7515
Zhihong HuState Key Laboratory of Virology, Wuhan Institute of Virology Chinese Academy of Sciences, Wuhan, Hubei, China.ORCID 0000-0002-1560-0928
Chinese Academy of Sciences · CNNankai University · CNXinjiang Uygur Autonomous Region Disease Prevention and Control Center · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

Antiviral AgentsBunyaviridaeEndonucleasesViral ProteinsBunyaviridae InfectionsEnzyme ActivationEnzyme InhibitorsHumansHydroxybutyratesPiperidinesStructure-Activity RelationshipAntiviral AgentsEndonucleasesEnzyme InhibitorsHydroxybutyratesL-742,001PiperidinesViral Proteinsbunyaviruscap-snatching endonucleasediketo acid inhibitorEbinur Lake virusstructure-activity relationship

Identifiers

PMID35266805
PMCPMC9006905
OpenAlexW4221012480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.