Evidence map›Paper›PMID 35266800›Full record

ArticleMolecular pain

Magnitude of peripheral sensory neuropathy and associated factors among HIV/AIDS clients receiving care at public health institutions, Northwest Ethiopia.

Getachew Y Yitbarek, Wondimnew D Addis, Fentaw T Dagnaw, Gashaw W Ayehu, Biruk D Melese, Tadeg J Amare, Anemut T Mulu, Wubet A Bayih, Berhanu K Ashagrie, Edgeit A Zewde and 6 more

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In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Getachew Y YitbarekDepartment of Biomedical Sciences, College of Health Science, 487509Debre Tabor University, Ethiopia.ORCID 0000-0001-9823-9981
Wondimnew D AddisDepartment of Public Health, College of Health Science, 487509Debre Tabor University, Ethiopia.
Fentaw T DagnawDepartment of Public Health, College of Health Science, 487509Debre Tabor University, Ethiopia.
Gashaw W AyehuDepartment of Biomedical Sciences, College of Health Science, 487509Debre Tabor University, Ethiopia.
Biruk D MeleseDepartment of Public Health, College of Health Science, 487509Debre Tabor University, Ethiopia.
Tadeg J AmareDepartment of Biomedical Sciences, College of Health Science, 487509Debre Tabor University, Ethiopia.
Anemut T MuluDepartment of Biomedical Sciences, College of Health Science, 487509Debre Tabor University, Ethiopia.
Wubet A BayihDepartment of Pediatric and Neonatal Nursing, College of Health Science, 487509Debre Tabor University, Ethiopia.
Berhanu K AshagrieDepartment of Biomedical Sciences, College of Health Science, 487509Debre Tabor University, Ethiopia.
Edgeit A ZewdeDepartment of Biomedical Sciences, College of Health Science, 487509Debre Tabor University, Ethiopia.
Tigabu MunyeDepartment of Adult Nursing, College of Health Science, 487509Debre Tabor University, Ethiopia.
Ermias S ChanieDepartment of Pediatric and Neonatal Nursing, College of Health Science, 487509Debre Tabor University, Ethiopia.
Workneh EbabuDepartment of Medicine, College of Health Science, 487509Debre Tabor University, Ethiopia.
Sintayehu AsnakewDepartment of Psychiatry, College of Health Science, 487509Debre Tabor University, Ethiopia.
Getachew ArageDepartment of Pediatric and Neonatal Nursing, College of Health Science, 487509Debre Tabor University, Ethiopia.
Assefa A TeshomeDepartment of Biomedical Sciences, College of Health Science, 487509Debre Tabor University, Ethiopia.
Debre Tabor University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the mid-1990s, the development of combination antiretroviral therapy converted HIV infection into a chronic condition, with newly diagnosed patients now living longer than the general population. HIV affects both the central and peripheral nerve systems, resulting in a variety of clinical problems, including peripheral neuropathy, which is a common neurological consequence. Despite this, there is a scarcity of data on the extent of peripheral sensory neuropathy and its underlying factors in Ethiopia, necessitating this study.

objectiveThe primary goal of this study is to assess the degree of peripheral sensory neuropathy and its related factors among HIV/AIDS clients on follow up at public health institutions in Northwest Ethiopia. METHODOLOGY: Institution based cross-sectional study was conducted from November 1 to 30 December 2020 at selected south Gondar zone public health institutions ART clinic. Multistage sampling technique was used to select the study participants. Standardized Questioner adapted from other study was used to collect the data. Moreover, Brief Peripheral Neuropathy Screening tool (BPNS) was used to assess peripheral sensory neuropathy. The data were entered with epi-data manager version 4.4 and analyzed using STATA version 16.

resultA total of 555 adult PLWHIV agreed to participate in the study, resulting in a response rate of 96.8%. The prevalence of Peripheral sensory neuropathy was 32.25, 95% CI (28.28, 36.26). The participant's age, DM comorbidity, viral load level, and disease clinical stage were all found to have a statistically significant association with peripheral sensory neuropathy.

conclusionPeripheral sensory neuropathy was incredibly common. Accordingly, peripheral sensory neuropathy was found considerably associated with age, viral load level, stage of the disease, and DM comorbidity. It is vital to integrate routine peripheral sensory neuropathy screening strategies for clients who are on ART follow up for prevention and early identification of the problem.

Indexed as

HIV InfectionsPeripheral Nervous System DiseasesAdultCross-Sectional StudiesEthiopiaHumansPublic Healthassociated factorsEthiopiaHIV/AIDSPeripheral neuropathy

Identifiers

PMID35266800
PMCPMC9016588
OpenAlexW4221134683

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.