ArticleThe Journal of infectious diseases2022
Antimicrobial Susceptibility Survey of Invasive Neisseria meningitidis, United States 2012-2016.
Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Graph-based and molecular modeling approaches to identify TpiA as a noval therapeutic target in Neisseria meningitidis.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Molecular basis of ampicillin resistance: combinatorial mechanisms and future strategies.World journal of microbiology & biotechnology · 2026Review
- Article
- Genomic surveillance of invasive Neisseria meningitidis isolates circulating in Paraguay, 2009-2021.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Observational
- Progression of antibiotic resistance inClinical microbiology reviews · 2025Review
- Genomic Diversity and Antimicrobial Susceptibility of Invasive Neisseria meningitidis in South Africa, 2016-2021.The Journal of infectious diseases · 2024Article
- Epidemiology and genetic diversity of invasive Neisseria meningitidis strains circulating in Portugal from 2003 to 2020.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Article
- Continuing genomic evolution of theMicrobial genomics · 2023Review
- Eculizumab for the treatment of glycine receptor antibody associated stiff-person syndrome.Journal of neurology · 2023Article
- Meningococcal Antibiotic Resistance: Molecular Characterization of Isolates from Patients with Invasive Meningococcal Disease (IMD) in Greece.Antibiotics (Basel, Switzerland) · 2023Article
- Recent Evolution of Susceptibility to Beta-Lactams inAntibiotics (Basel, Switzerland) · 2023Article
- Antibiotic Susceptibility Profile for the USOpen forum infectious diseases · 2023Article
- Meningococcal disease in North America: Updates from the Global Meningococcal Initiative.The Journal of infection · 2022Review
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8 authors.
Funding
Abstract
backgroundHistorically, antimicrobial resistance has been rare in US invasive meningococcal disease cases.
methodsMeningococcal isolates (n = 695) were collected through population-based surveillance, 2012-2016, and national surveillance, 2015-2016. Antimicrobial susceptibility was assessed by broth microdilution. Resistance mechanisms were characterized using whole-genome sequencing.
resultsAll isolates were susceptible to 6 antibiotics (cefotaxime, ceftriaxone, meropenem, rifampin, minocycline, and azithromycin). Approximately 25% were penicillin or ampicillin intermediate; among these, 79% contained mosaic penA gene mutations. Less than 1% of isolates were penicillin, ampicillin, ciprofloxacin, or levofloxacin resistant.
conclusionsPenicillin- and ampicillin-intermediate isolates were common, but resistance to clinically relevant antibiotics remained rare.
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