Evidence map›Paper›PMID 35266063›Full record

ArticleClinical & experimental metastasis2022

PSMA-guided metastases directed therapy for bone castration sensitive oligometastatic prostate cancer: a multi-institutional study.

Rosario Mazzola, Francesco Cuccia, Edoardo Pastorello, Matteo Salgarello, Giulio Francolini, Lorenzo Livi, Luca Triggiani, Stefano Maria Magrini, Gianluca Ingrosso, Cynthia Aristei and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical & experimental metastasis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Comparison of Digital versus AnalogDiagnostics (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Rosario MazzolaAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.
Francesco CucciaAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy. francesco.cuccia@sacrocuore.it.ORCID 0000-0003-0390-9511
Edoardo PastorelloAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.
Matteo SalgarelloNuclear Medicine Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.
Giulio FrancoliniRadiotherapy Unit, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy.
Lorenzo LiviRadiotherapy Unit, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy.
Luca TriggianiDepartment of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Stefano Maria MagriniDepartment of Radiation Oncology, University and Spedali Civili Hospital, Brescia, Italy.
Gianluca IngrossoRadiation Oncology Section, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Cynthia AristeiRadiation Oncology Section, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Ciro FranzeseDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele-Milan, Italy.
Marta ScorsettiDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele-Milan, Italy.
Filippo AlongiAdvanced Radiation Oncology Department, IRCCS Sacro Cuore Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.
Ospedale Sacro Cuore Don Calabria · ITAzienda Ospedaliero-Universitaria Careggi · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITHumanitas University · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the outcomes of a cohort of bone oligometastatic prostate cancer patients treated with PSMA-PET guided stereotactic body radiotherapy (SBRT). From April 2017 to January 2021, 40 patients with oligorecurrent prostate cancer detected by PSMA-PET were treated with SBRT for bone oligometastases. Concurrent androgen deprivation therapy was an exclusion criterion. A total of 56 prostate cancer bone oligometastases were included in the present analysis. In 28 patients (70%), oligometastatic disease presented as a single lesion, two lesions in 22.5%, three lesions in 5%, four lesions in 2.5%. 30.3% were spine-metastases, while 69.7% were non-spine metastases. SBRT was delivered for a median dose of 30 Gy (24-40 Gy) in 3-5 fractions, with a median EQD

Indexed as

Prostatic NeoplasmsRadiosurgeryAndrogen AntagonistsCastrationHumansMaleProgression-Free SurvivalRetrospective StudiesAndrogen AntagonistsOligometastasesPSMA-PETStereotactic body radiotherapy

Identifiers

PMID35266063
OpenAlexW4220674980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.