Trial reportEuropean journal of nutrition2022
Impact of energy drink versus coffee consumption on periodic repolarization dynamics: an interventional study.
Trial report in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04886869 (Impact of Caffeine Consumption on Markers of the Autonomic Nervous System), which is not on this map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Caffeine Consumption on Markers of the Autonomic Nervous System
Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- [Successful resuscitation after energy drink consumption in a patient with unknown right ventricular dysplasia].Die Anaesthesiologie · 2024Article
- Biomarker Periodic Repolarization Dynamics Indicates Enhanced Risk for Arrhythmias and Sudden Cardiac Death in Myocardial Infarction in Pigs.Journal of the American Heart Association · 2024Article
- The Dark Side of Energy Drinks: A Comprehensive Review of Their Impact on the Human Body.Nutrients · 2023Review
- Inequalities in energy drink consumption among UK adolescents: a mixed-methods study.Public health nutrition · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCaffeinated beverages are consumed daily throughout the world. Caffeine consumption has been linked to dysfunction of the autonomic nervous system. However, the exact effects are still insufficiently understood.
methodsSixteen healthy individuals were included in the present non-randomized cross-over interventional study. All study subjects consumed a commercial energy drink (containing 240 mg caffeine), and in a second independent session coffee (containing 240 mg caffeine). High-resolution digital ECGs in Frank-lead configuration were recorded at baseline before consumption, and 45 min after consumption of the respective beverage. Using customized software, we assessed ECG-based biomarker periodic repolarization dynamics (PRD), which mirrors the effect of efferent cardiac sympathetic activity on the ventricular myocardium.
resultsThe consumption of energy drinks resulted in an increase in PRD levels (3.64 vs. 5.85 deg
conclusionOur data suggests that sympathetic activation after consumption of caffeinated beverages is independent from caffeine and might be mediated by other substances. TRIAL NUMBER: NCT04886869, 13 May 2021, retrospectively registered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.