Evidence map›Paper›PMID 35266017›Full record

SynthesisMolecular medicine reports2022

Τelomerase inhibitors and activators in aging and cancer: A systematic review.

Persefoni Fragkiadaki, Elisavet Renieri, Katerina Kalliantasi, Elisavet Kouvidi, Evita Apalaki, Elena Vakonaki, Charalampos Mamoulakis, Demetrios A Spandidos, Aristidis Tsatsakis

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Molecular medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

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  10. mAmerican journal of cancer research · 2024
    Article
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  19. Stem Cell Models for Cancer Therapy.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Persefoni FragkiadakiLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Elisavet RenieriLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Katerina KalliantasiLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Elisavet KouvidiGenesis Genoma Lab, Genetic Diagnosis, Clinical Genetics and Research, Athens 15232, Greece.
Evita ApalakiDepartment of Immunology, Genetics and Pathology (IGP), Uppsala University, 75105 Uppsala, Sweden.
Elena VakonakiLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Charalampos MamoulakisDepartment of Urology, University General Hospital of Heraklion, University of Crete, 71003 Heraklion, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, School of Medicine, University of Crete, 71003 Heraklion, Greece.
Aristidis TsatsakisLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
University of Crete · GRUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main aim of the present systematic review was to summarize the most frequently used telomerase regulators with an impact on aging and cancer that are referred to in

Indexed as

NeoplasmsTelomeraseAgingEnzyme InhibitorsHumansTelomereEnzyme InhibitorsTelomeraseactivatorsinhibitorsregulatorstelomerase enzymetelomere length

Identifiers

PMID35266017
PMCPMC8941523
OpenAlexW4220652528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.