Evidence map›Paper›PMID 35265853›Full record

ArticleCritical care explorations2022

Increasing Mortality in Venovenous Extracorporeal Membrane Oxygenation for COVID-19-Associated Acute Respiratory Distress Syndrome.

Jacob A Braaten, Zachary R Bergman, Jillian K Wothe, Arianna E Lofrano, Luke J Matzek, Melissa Doucette, Ramiro Saavedra-Romero, John K Bohman, Matthew E Prekker, Elizabeth R Lusczek and 1 more

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jacob A BraatenUniversity of Minnesota, Medical School, Minneapolis, MN.
Zachary R BergmanDepartment of Surgery, University of Minnesota, Minneapolis, MN.
Jillian K WotheUniversity of Minnesota, Medical School, Minneapolis, MN.
Arianna E LofranoDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN.
Luke J MatzekDepartment of Critical Care Medicine, Abbott Northwestern Hospital, Minneapolis, MN.
Melissa DoucetteDepartment of Emergency Medicine, Hennepin Healthcare, Minneapolis, MN.
Ramiro Saavedra-RomeroDepartment of Emergency Medicine, Hennepin Healthcare, Minneapolis, MN.
John K BohmanDepartment of Critical Care Medicine, Abbott Northwestern Hospital, Minneapolis, MN.
Matthew E PrekkerDepartment of Internal Medicine, Hennepin Healthcare, Minneapolis, MN.
Elizabeth R LusczekDepartment of Surgery, University of Minnesota, Minneapolis, MN.
Melissa E BrunsvoldDepartment of Surgery, University of Minnesota, Minneapolis, MN.
University of Minnesota · USHennepin Healthcare Research Institute · USMayo Clinic in Arizona · USUniversity of Minnesota Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDetermine the factors associated with mortality in venovenous extracorporeal membrane oxygenation (V-V ECMO) patients with COVID-19 infection and provide an updated report of clinical outcomes for patients treated with V-V ECMO for COVID-19 in Minnesota.

designMulticenter prospective observational study.

settingThe four adult Extracorporeal Life Support Organization-certified Centers of Excellence in Minnesota. PATIENTS: A total of 100 patients treated with V-V ECMO for COVID-19-associated acute respiratory distress syndrome (ARDS) from March 2020 to May 2021.

interventionsNot applicable. MEASUREMENTS AND MAIN

resultsThe primary outcome was 60-day survival for patients treated with V-V ECMO for COVID-19. Outcomes of patients treated from November 2020 to May 2021(cohort 2) were compared with data from a previous cohort of patients, collected from March 2020 to October 2020 (cohort 1). The data from both cohorts were merged into a single dataset (Combined Cohort). Survival on V-V ECMO due to COVID-19-associated ARDS significantly decreased after October 2020 (63% vs 41%;

conclusionsThere was a significant increase in mortality for patients treated with V-V ECMO for COVID-19-associated ARDS in cohort 2 compared with cohort 1. Further research is required to determine the cause of the worsening trend in mortality.

Indexed as

acute respiratory distress syndromeCOVID-19mortalitypandemicsteroidsvenovenous extracorporeal membrane oxygenation

Identifiers

PMID35265853
PMCPMC8901198
OpenAlexW4214952666

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.