Evidence map›Paper›PMID 35265845›Full record

ArticleAdvances in pharmacological and pharmaceutical sciences2022

Evaluation of Hepatoprotective Potential of Polyherbal Preparations in CCl

Rayhana Begum, Sonia Akther Papia, Mst Marium Begum, Hongbin Wang, Rubaba Karim, Rebeka Sultana, Priyanka Rani Das, Taslima Begum, Md Ragibul Islam, Nargis Manwar and 1 more

Open access · goldAbstract read
In one paragraph

Article in Advances in pharmacological and pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Rayhana BegumDepartment of Pharmacy, Primeasia University, Dhaka, Bangladesh.ORCID https://orcid.org/0000-0002-9490-3299
Sonia Akther PapiaDepartment of Pharmacy, Primeasia University, Dhaka, Bangladesh.
Mst Marium BegumDepartment of Pharmacy, East West University, Aftabnagar, Dhaka-1212, Bangladesh.
Hongbin WangDepartment of Pharmaceutical and Biomedical Sciences, College of Pharmacy, California Northstate University, CA, USA.
Rubaba KarimDepartment of Pharmacy, Primeasia University, Dhaka, Bangladesh.
Rebeka SultanaSchool of Molecular Medical Sciences, University of Nottingham, Nottingham, UK.
Priyanka Rani DasDepartment of Pharmacy, Primeasia University, Dhaka, Bangladesh.
Taslima BegumDepartment of Pharmacy, Primeasia University, Dhaka, Bangladesh.
Md Ragibul IslamDepartment of Pharmacy, Primeasia University, Dhaka, Bangladesh.
Nargis ManwarDepartment of Pharmacy, Primeasia University, Dhaka, Bangladesh.
Md Sohanur RahmanDepartment of Biochemistry and Molecular Biology, Trust University, Barishal, Ruiya, Nobogram Road, Barishal 8200, Bangladesh.ORCID https://orcid.org/0000-0002-1133-268X
Primeasia University · BDCalifornia Northstate University · USEast West University · BDUniversity of Barishal · BDUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Polyherbal formulations (PLFs) have been widely used for liver protection, treatment for hepatic dysfunction, and regeneration. They can also enhance appetite and protect the gastrointestinal tract from injury. In spite of the prevalent use, there is a need of scientific evidence on their effectiveness and safety. The objective of the present study was to assess the hepatoprotective effect of polyherbal formulations (commercially available in Bangladesh namely Heptaliv, Holyliv, Icturn, and J-deenar) in CCl Methods: In this study, Swiss albino mice were treated for 7 days with distilled water or PLFs (2.6 and 5.2 ml/kg body weight/day, per os.) followed by single subcutaneous injection of CCl Results: CCl Conclusion: Our results confirmed that polyherbal formulations (Icturn and J-deenar) can significantly prevent CCl

Identifiers

PMID35265845
PMCPMC8898809
OpenAlexW4214766773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.