Evidence map›Paper›PMID 35265783›Full record

ArticleJournal of the Endocrine Society2022

Pediatric Diabetes on the Rise: Trends in Incident Diabetes During the COVID-19 Pandemic.

Rachel Modarelli, Salma Sarah, Megan E Ramaker, Mboli Bolobiongo, Robert Benjamin, Pinar Gumus Balikcioglu

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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  16. Glycemic Control and Bone in Diabetes.Current osteoporosis reports · 2022
    Review
  17. Article
  18. COVID-19 and diabetes in children.Annals of pediatric endocrinology & metabolism · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rachel ModarelliDepartment of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.
Salma SarahDivision of Pediatric Endocrinology and Diabetes, Duke University Medical Center, Durham, NC 27705, USA.
Megan E RamakerDuke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA.ORCID https://orcid.org/0000-0003-2183-2319
Mboli BolobiongoDuke School of Medicine, Master of Biomedical Sciences, Durham, NC 27710, USA.
Robert BenjaminDivision of Pediatric Endocrinology and Diabetes, Duke University Medical Center, Durham, NC 27705, USA.
Pinar Gumus BalikciogluDivision of Pediatric Endocrinology and Diabetes, Duke University Medical Center, Durham, NC 27705, USA.ORCID https://orcid.org/0000-0002-5259-9196
Duke Medical Center · USDuke University · US

Funding

Serotonin as a Novel Biomarker for Progression to Type 2 Diabetes in Obese AdolescentsK23DK117067 · NIDDK · DUKE UNIVERSITY · PI GUMUS BALIKCIOGLU, PINAR · 2018 to 2021
$847k
NIDDK NIH HHS K23 DK117067
6 · The paper itself

Abstract

Context: The effects of the coronavirus disease 2019 (COVID-19) pandemic on the incident cases of pediatric type 1 diabetes (T1D) and type 2 diabetes (T2D) are not clear. Objective: To identify trends in incidence and presentation of pediatric new-onset T1D and T2D during the COVID-19 pandemic. Methods: A retrospective chart review was conducted. Demographics, anthropometrics, and initial laboratory results from patients ages 0 through 21 years who presented with new-onset diabetes to a pediatric tertiary care center were recorded. Results: During the pandemic, incident cases of pediatric T1D increased from 31 in each of the prior 2 years to 46; an increase of 48%. Incident cases of pediatric T2D increased by 231% from 2019 to 2020. The number of incident cases of pediatric T2D increased significantly more than the number of incident cases of pediatric T1D ( Conclusions: There were more incident pediatric T1D and T2D cases as well as an increase in DKA severity in T2D at presentation during the COVID-19 pandemic. More importantly, incident T2D cases were higher than the incident T1D during the pandemic. This clearly suggests a disruption and change in the pediatric diabetes trends with profound individual and community health consequences.

Indexed as

COVID-19diabetic ketoacidosispediatric diabetestype 1 diabetestype 2 diabetes

Identifiers

PMID35265783
PMCPMC8900286
OpenAlexW4213120620

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.