SynthesisFrontiers in surgery2022
Comparison of Clinical Features and Outcomes of Appendectomy in Elderly vs. Non-Elderly: A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Machine learning constructs a diagnostic prediction model for gangrenous perforation of acute appendicitis in elderly patients.BMC surgery · 2026Article
- A Hybrid Model with Quantum Feature Map Based on CNN and Vision Transformer for Clinical Support in Diagnosis of Acute Appendicitis.Biomedicines · 2026Article
- An Observational Review of Tonsillectomy and Appendectomy Procedures Conducted at a Tertiary Care Hospital.Cureus · 2025Article
- Influence of sarcopenia and frailty in the management of elderly patients with acute appendicitis.World journal of clinical cases · 2024Article
- Factors associated with early inhospital adverse outcome following surgery for acute appendicitis in Uganda: a multicenter cohort.Perioperative medicine (London, England) · 2024Article
- Acute appendicitis over the age of 50: The evaluation of the impact of clinical variables on operative and post-operative outcomes.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The objective of this study is to compare clinical and surgical outcomes of appendectomy among elderly and non-elderly subjects. Methods: A systematic search was conducted on PubMed, Scopus, and Google academic databases. Studies, observational in design, that compared peri-and postoperative outcomes of appendectomy, in patients with acute appendicitis, between elderly and non-elderly/younger subjects were considered for inclusion. Statistical analysis was performed using STATA software. Results: A total of 15 studies were included. Compared to non-elderly patients, those that were elderly had an increased risk of complicated appendicitis [relative risk (RR), 2.38; 95% CI: 2.13, 2.66], peritonitis [RR, 1.88; 95% CI: 1.36, 2.59], and conversion from laparoscopic to open appendectomy [RR, 3.02; 95% CI: 2.31, 3.95]. The risk of overall postoperative complications [RR, 2.59; 95% CI: 2.19, 3.06], intra-abdominal abscess [RR, 1.84; 95% CI: 1.15, 2.96], wound infection [RR, 3.80; 95% CI: 2.57, 5.61], and use of postoperative drainage [RR, 1.14; 95% CI: 1.09, 1.19] was higher among the elderly. The risk of readmission (30 days) [RR, 1.61; 95% CI: 1.16, 2.24] and mortality (30 days) [RR, 12.48; 95% CI: 3.65, 42.7] was also higher among elderly. Conclusions: Findings suggest an increased risk of peri-and postoperative complications among elderly subjects undergoing appendectomy, compared to non-elderly subjects. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier: CRD42021286157.
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