Evidence map›Paper›PMID 35265622›Full record

ReviewFrontiers in cell and developmental biology2022

Using

Joyce van de Leemput, Pei Wen, Zhe Han

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Mechanotransduction and the Integrity of the Slit Diaphragm.Journal of the American Society of Nephrology : JASN · 2025
    Article
  6. Piezo, Nephrocyte Function, and Slit Diaphragm Maintenance in Drosophila.Journal of the American Society of Nephrology : JASN · 2025
    Article
  7. The Power of Drosophila in Modeling Cancer Cachexia.Advances in experimental medicine and biology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joyce van de LeemputCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Pei WenCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Zhe HanCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
University of Maryland, Baltimore · US

Funding

Modeling Nephrotic Syndrome in Drosophila NephrocytesR01DK098410 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI HAN, ZHE · 2014 to 2022
$3.3M
Integrating Drosophila and human podocyte studies to discover APOL1 renal toxicity mechanism and therapeutic targetsR01DK120908 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI HAN, ZHE · 2019 to 2022
$1.4M
NIDDK NIH HHS R01 DK098410NIDDK NIH HHS R01 DK120908
6 · The paper itself

Abstract

The podocyte slit diaphragm (SD) is an essential component of the glomerular filtration barrier and its disruption is a common cause of proteinuria and many types of kidney disease. Therefore, better understanding of the pathways and proteins that play key roles in SD formation and maintenance has been of great interest. Podocyte and SD biology have been mainly studied using mouse and other vertebrate models. However, vertebrates are limited by inherent properties and technically challenging

Indexed as

apical-basal polaritycytoskeletonDrosophila nephrocytesendocytosis and exocytosisglomerular diseaseskidneymammalian podocytesslit diaphragm

Identifiers

PMID35265622
PMCPMC8898902
OpenAlexW4212877061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.