ArticleFrontiers in chemistry2022
AuPt Bimetallic Nanozymes for Enhanced Glucose Catalytic Oxidase.
Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Sustainable Ag-Cu bimetallic nanozymes derived from Juglans regia husk exhibit multifunctional catalytic, antimicrobial, and antioxidant activities.Scientific reports · 2026Article
- A Review of the Activity Regulation of Au and Pt Bimetallic Nanozymes and Their Application in Food Safety Analysis.Biosensors · 2026Review
- pH-switchable AuPt@CeOMikrochimica acta · 2026Article
- Beyond antibiotics: engineered metal nanozymes for resistance-evading antibacterial therapy.Journal of nanobiotechnology · 2026Review
- Engineered metallic hybrid nanozyme for advanced inflammatory disease therapy.Materials today. Bio · 2025Review
- Propelling gold nanozymes: catalytic activity and biosensing applications.Analytical and bioanalytical chemistry · 2024Review
- Au@Pt nanoparticles-based signal-enhanced lateral flow immunoassay for ultrasensitive naked-eye detection of SARS-CoV-2.Mikrochimica acta · 2024Article
- Carbon nanotubes: a powerful bridge for conductivity and flexibility in electrochemical glucose sensors.Journal of nanobiotechnology · 2023Review
- Smart Biomimetic Nanozymes for Precise Molecular Imaging: Application and Challenges.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Nanozyme-assisted amplification-free CRISPR/Cas system realizes visual detection.Frontiers in bioengineering and biotechnology · 2023Review
- Progress and perspectives of platinum nanozyme in cancer therapy.Frontiers in chemistry · 2022Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Au metal nanoparticles as artificial nanozymes have attracted wide interest in biotechnology due to high stability and easy synthesis. Unfortunately, its catalytic activity is limited by the uniform surface electron distribution, fundamentally affecting the oxidation efficiency of glucose. Here, we synthesized AuPt bimetallic nanoparticles with unique surface electron structure due to the coupling effect of the two metal components, achieving improved glucose catalytic oxidase. Because of the effective work function difference between the two metals in AuPt, the electrons will transfer from Au to accumulate on Pt, simultaneously contributing to the substantial enhancement of Au-induced glucose oxidase and Pt-induced catalase performance. We systematically studied the enzyme-catalytic efficiency of AuPt with varied two metal proportions, in which Au:Pt at 3:1 showed the highest catalytic efficiency of glucose oxidase in solution. The AuPt nanoparticles were further co-cultured with cells and also showed excellent biological activity for glucose oxidase. This work demonstrates that the physicochemical properties between different metals can be exploited for engineering high-performance metal nanoparticle-based nanozymes, which opens up a new way to rationally design and optimize artificial nanozymes to mimic natural enzymes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.