ArticleAnnals of maxillofacial surgery
Single Nucleotide Polymorphisms in Runt-related Transcription Factor 2 and Bone Morphogenetic Protein 2 Impact on Their Maxillary and Mandibular Gene Expression in Different Craniofacial Patterns - A Comparative Study.
Article in Annals of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Association between single-nucleotide polymorphisms in endochondral development-related genes and 3D phenotypic variation of the cranial base.Head & face medicine · 2026Article
- Predictive model of delayed union of tibial and fibular fractures based on PGC-1α, NOS, and Runx2.European journal of medical research · 2025Article
- BMP2 rs1005464 is associated with mandibular condyle size variation.Scientific reports · 2024Article
- Single Nucleotide Polymorphisms in RUNX2 and BMP2 contributes to different vertical facial profile.PloS one · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This study aimed to evaluate if single nucleotide polymorphisms (SNPs) in runt-related transcription factor 2 ( Materials and Methods: Lateral cephalometric radiographs were used to classify facial phenotypes based on Steiner's ANB and Ricketts' NBa-PtGn angles. Bone samples from 21 patients collected during orthognathic surgery were used for the gene expression assays. DNA from 129 patients was used for genotyping the SNPs rs59983488 and rs1200425 in Results: A statistically significant difference was observed in the relative BMP2 expression in the mandible between Class I and III participants ( Discussion: In conclusion, BMP2 is expressed differently in the mandible of Class I and Class III participants. Genetic polymorphisms in
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