Evidence map›Paper›PMID 35265317›Full record

ArticleInternational journal of inflammation2022

Cytotoxic Activity and Lymphocyte Subtypes in Mice Selected for Maximal and Minimal Inflammatory Response after Transplantation of B16F10 and S91 Melanoma Cells.

Lindsey Castoldi, Graziela Gorete Romagnoli, Marjorie de Assis Golim, Orlando Garcia Ribeiro, Olga Célia Martinez Ibañez, Durvanei Augusto Maria, Andréa Vanessa Pinto Domeneghini, Maria Carolina Gameiro, Priscila Raquel Martins, Martha Maria Mischan and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Lindsey CastoldiHealth Sciences Institute, Federal University of Mato Grosso-UFMT, Sinop, Mato Grosso, Brazil.ORCID https://orcid.org/0000-0001-9678-5815
Graziela Gorete RomagnoliDepartment of Chemical and Biological Sciences, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil.
Marjorie de Assis GolimHemocentro Division, School of Medicine of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil.
Orlando Garcia RibeiroLaboratory of Immunogenetics, Institute Butantan, São Paulo, São Paulo, Brazil.
Olga Célia Martinez IbañezLaboratory of Immunogenetics, Institute Butantan, São Paulo, São Paulo, Brazil.
Durvanei Augusto MariaLaboratory of Biochemistry and Biophysics, Institute Butantan, São Paulo, São Paulo, Brazil.
Andréa Vanessa Pinto DomeneghiniCentral Paulista University Center - UNICEP, São Carlos, São Paulo, Brazil.
Maria Carolina GameiroDepartment of Chemical and Biological Sciences, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil.
Priscila Raquel MartinsDepartment of Chemical and Biological Sciences, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil.
Martha Maria MischanDepartment of Biostatistics, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil.
Ramon KanenoDepartment of Chemical and Biological Sciences, Institute of Bioscience of Botucatu, São Paulo State University-UNESP, Botucatu, São Paulo, Brazil.
Universidade Estadual Paulista (Unesp) · BRInstituto Butantan · BRCentro Universitário Central Paulista · BRUniversidade do Oeste Paulista · BRUniversidade Federal de Mato Grosso · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIRmax and AIRmin mice strains were selected according to the intensity of their acute inflammatory responsiveness. Previous studies have shown that AIR mice differ in their resistance to chemically induced skin tumors and in the development of melanoma metastases, in addition to differences in neutrophil and NK cells activity. In the present work, we aimed to evaluate whether the difference of susceptibility to murine melanoma is associated with NK cytotoxic activity against Yac.1 cells and lymphocyte subsets. Mice were subcutaneously inoculated with B16F10 or S91 melanoma cells. After 7, 14, or 30 days, the animals were euthanized to analyze the number of lymphocyte subsets, cytotoxic activity, and number of cytokine-producing spleen cells. AIRmax mice presented a higher number of CD4

Identifiers

PMID35265317
PMCPMC8901355
OpenAlexW4214558588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.